[HTML][HTML] Macrophage-mediated inflammation in skin wound healing

A Hassanshahi, M Moradzad, S Ghalamkari, M Fadaei… - Cells, 2022 - mdpi.com
Macrophages are key immune cells that respond to infections, and modulate
pathophysiological conditions such as wound healing. By possessing phagocytic activities …

Macrophage and fibroblast interactions in biomaterial‐mediated fibrosis

CE Witherel, D Abebayehu, TH Barker… - Advanced healthcare …, 2019 - Wiley Online Library
Biomaterial‐mediated inflammation and fibrosis remain a prominent challenge in designing
materials to support tissue repair and regeneration. Despite the many biomaterial …

Mesenchymal stem cell-derived exosomes loaded with miR-155 inhibitor ameliorate diabetic wound healing

P Gondaliya, AA Sayyed, P Bhat, M Mali… - Molecular …, 2022 - ACS Publications
Diabetic wounds are one of the debilitating complications that affect up to 20% of diabetic
patients. Despite the advent of extensive therapies, the recovery rate is unsatisfactory, and …

The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing

X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

[HTML][HTML] The immune-centric revolution in the diabetic foot: monocytes and lymphocytes role in wound healing and tissue regeneration—a narrative review

L Rehak, L Giurato, M Meloni, A Panunzi… - Journal of Clinical …, 2022 - mdpi.com
Monocytes and lymphocytes play a key role in physiologic wound healing and might be
involved in the impaired mechanisms observed in diabetes. Skin wound macrophages are …

[HTML][HTML] Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway

N Ebrahim, AA Dessouky, O Mostafa… - Stem cell research & …, 2021 - Springer
Background Diabetic foot ulceration is a serious chronic complication of diabetes mellitus
characterized by high disability, mortality, and morbidity. Platelet-rich plasma (PRP) has …

Ly6CHi Blood Monocyte/Macrophage Drive Chronic Inflammation and Impair Wound Healing in Diabetes Mellitus

A Kimball, M Schaller, A Joshi, FM Davis… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Wound monocyte-derived macrophage plasticity controls the initiation and
resolution of inflammation that is critical for proper healing, however, in diabetes mellitus, the …

Notch signalling: multifaceted role in development and disease

N Sachan, V Sharma, M Mutsuddi… - The FEBS …, 2024 - Wiley Online Library
Notch pathway is an evolutionarily conserved signalling system that operates to influence an
astonishing array of cell fate decisions in different developmental contexts. Notch signalling …

Molecular pathways of NF-ĸB and NLRP3 inflammasome as potential targets in the treatment of inflammation in diabetic wounds: A review

HX Teh, SJ Phang, ML Looi, UR Kuppusamy… - Life Sciences, 2023 - Elsevier
Diabetic wounds are slow healing wounds characterized by disordered healing processes
and frequently take longer than three months to heal. One of the defining characteristics of …

[HTML][HTML] The flavonoid quercetin ameliorates liver inflammation and fibrosis by regulating hepatic macrophages activation and polarization in mice

X Li, Q Jin, Q Yao, B Xu, L Li, S Zhang… - Frontiers in …, 2018 - frontiersin.org
At present, there are no effective antifibrotic drugs for patients with chronic liver disease;
hence, the development of antifibrotic therapies is urgently needed. Here, we performed an …