Beta-thalassemias are a group of hereditary blood disorders characterized by anomalies in
the synthesis of the beta chains of hemoglobin resulting in variable phenotypes ranging from …

Iron-Chelating Therapy for Transfusional Iron Overload | New England Journal of Medicine Skip
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Thalassemia major and sickle cell disease are the two most widely disseminated hereditary
hemoglobinopathies in the world. The outlook for affected individuals has improved in recent …

Quantitative imaging biomarkers of liver disease measured by using MRI and US are
emerging as important clinical tools in the management of patients with chronic liver disease …

Featuring hundreds of full-color photomicrographs, Rodak's Hematology: Clinical Principles
and Applications, 5th Edition prepares you for a job in the clinical lab by exploring the …

Our intention is to demystify the MR quantification of hepatic iron (ie, the liver iron
concentration) and give you a step-by-step approach by answering the most pertinent …

Patients with β-thalassemia major (TM) and other refractory anemias requiring regular blood
transfusions accumulate iron that damages the liver, endocrine system, and most importantly …

Background The quantity of iron in body is carefully regulated, primarily by control of iron
absorption, and excess total body iron can be extremely toxic. Since humans have no …

BACKGROUND: Most dialysis patients receiving erythropoesis-stimulating agents (ESA)
also receive parenteral iron supplementation. There are few data on the risk of …

Transfusional iron overload is a major target in the care of patients with transfusion-
dependent thalassemia (TDT) and other refractory anemias. Iron accumulates in the liver …