Spontaneous dimerization of EGF receptors (EGFR) and dysregulation of EGFR signaling
has been associated with the development of different cancers. Under normal physiological …

Background Tumor resistance to cisplatin represents a major clinical challenge, particularly
in bladder cancer (BC). ANXA6 is a member of annexin family, and its role in cisplatin …

Protein kinase C (PKC) comprises a family of highly related serine/threonine protein kinases
involved in multiple signaling pathways, which control cell proliferation, survival, and …

The discovery of protein kinase playing key roles in cancer formation and progression has
triggered great interest and stimulated intense research on signaling pathways to develop …

The serine protease prostasin is a negative regulator of lipopolysaccharide-induced
inflammation and has a role in the regulation of cellular immunity. Prostasin expression in …