Chromones as a privileged scaffold in drug discovery: A review

RS Keri, S Budagumpi, RK Pai… - European Journal of …, 2014 - Elsevier
The chromone and its derivatives are the most important heterocyclic compounds, which is a
common and integral feature of a variety of natural products and medicinal agents. These …

Oxidative stress in carcinogenesis: new synthetic compounds with dual effects upon free radicals and cancer.

B Tekiner-Gulbas, AD Westwell… - Current medicinal …, 2013 - ingentaconnect.com
DNA mutation is a very important step in carcinogenesis and elevated levels of oxidative
DNA damage have been monitored in a variety of tumors. The discovery of the role of free …

In Vitro Evaluation of Selected Benzimidazole Derivatives as an Antioxidant and Xanthine Oxidase Inhibitors

SH Nile, B Kumar, SW Park - Chemical biology & drug design, 2013 - Wiley Online Library
2‐Aryl‐1‐arylmethyl‐1 H‐benzimidazole derivatives having different side chains on the
structure were examined in vitro for their antioxidant abilities by 2, 2‐diphenyl‐1‐picryl …

Experimental and theoretical (FT-IR, FT-Raman, UV–vis, NMR) spectroscopic analysis and first order hyperpolarizability studies of non-linear optical material:(2E)-3-[4 …

A Kumar, V Deval, P Tandon, A Gupta… - Spectrochimica Acta Part …, 2014 - Elsevier
A combined experimental and theoretical investigation on FT-IR, FT-Raman, NMR, UV–vis
spectra of a chalcone derivative (2E)-3-[4-(methylsulfanyl) phenyl]-1-(4-nitrophenyl) prop-2 …

[HTML][HTML] HPTLC analysis, antioxidant and antigout activity of Indian plants

SH Nile, SW Park - Iranian Journal of Pharmaceutical Research …, 2014 - ncbi.nlm.nih.gov
The HPTLC analysis, antioxidant, and antigout activity of Asparagus racemosus, Withania
somnifera, Vitex negundo, Plumbago zeylanica, Butea monosperma and Tephrosia …

[PDF][PDF] Synthesis and pharmacological applications of chalcones: A review

DI Ugwu, BE Ezema, UC Okoro, FU Eze… - Int. J. Chem …, 2015 - researchgate.net
Chalcones are pharmacologically active compounds, chemically known as derivatives of 1,
3-diphenylprop-2-en-1-one. They have found applications as anticancer, anti-diabetics, anti …

In Vitro Anti-inflammatory and Xanthine Oxidase Inhibitory Activity of Tephrosia purpurea Shoot Extract

SH Nile, CN Khobragade - Natural product communications, 2011 - journals.sagepub.com
The methanolic extract of Tephrosia purpurea (Leguminosae) shoots was evaluated in-vitro
for its anti-inflammatory and xanthine oxidase inhibitory activity. Anti-inflammatory activity …

Homology modeling and docking study of xanthine oxidase of Arthrobacter sp. XL26

RG Bodade, SD Beedkar, AV Manwar… - International journal of …, 2010 - Elsevier
Hyperuricemia is a condition of defective purine metabolism characterized with elevated
serum uric acid (UA) level that further leads to gout and gouty nephrolithiasis disorders. Gout …

Phytochemical analysis, antioxidant and xanthine oxidase inhibitory activity of Tephrosia purpurea Linn. root extract

SH Nile, CN Khobragade - 2011 - nopr.niscpr.res.in
An attempt has been made to search for xanthine oxidase (XO) inhibitors from the root
extracts of Tephrosia purpurea Linn. which is traditionally used in folk medicine in India …

Experimental and computational study on molecular structure, natural bond orbital and natural hybrid orbital analysis of non-linear optical material trans-3-(o …

V Karunakaran, V Balachandran - Journal of Molecular Structure, 2013 - Elsevier
Fourier transform infrared and Fourier transform Raman spectra of trans-3-(o-hydroxyphenyl-
1-phenyl)-2-propen-1-one (or simply 2-hydroxychalcone) were recorded in the regions 4000 …