Leishmaniasis in humans: drug or vaccine therapy?

M Ghorbani, R Farhoudi - Drug design, development and therapy, 2017 - Taylor & Francis
Leishmania is an obligate intracellular pathogen that invades phagocytic host cells.
Approximately 30 different species of Phlebotomine sand flies can transmit this parasite …

Nanovaccine: An emerging strategy

A Das, N Ali - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Vaccination is so far the most effective way of eradicating infections. Rapidly
emerging drug resistance against infectious diseases and chemotherapy-related toxicities in …

Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb

F Lallemand, P Daull, S Benita… - Journal of drug …, 2012 - Wiley Online Library
Topical ophthalmic delivery of active ingredients can be achieved using cationic
nanoemulsions. In the last decade, Novagali Pharma has successfully developed and …

A state-of-the-art review on solid lipid nanoparticles as a nanovaccines delivery system

M Assefi, M Ataeinaeini, A Nazari, A Gholipour… - Journal of Drug Delivery …, 2023 - Elsevier
In the design of vaccine generation, significant attempts have been made to produce novel
vaccines and, as well, to increase the effectiveness of available vaccines versus particular …

Solid lipid nanoparticles: a promising nanomaterial in drug delivery

K Rajpoot - Current pharmaceutical design, 2019 - ingentaconnect.com
The solid lipid nanoparticles (SLNs) usually consists of active drug molecules along with
solid lipids, surfactants, and/or co-surfactants. They possess some potential features such as …

Applications of lipid nanoparticles in gene therapy

A del Pozo-Rodriguez, MÁ Solinís… - European Journal of …, 2016 - Elsevier
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have been
recognized, among the large number of non-viral vectors for gene transfection, as an …

[HTML][HTML] Current status of nanoscale drug delivery and the future of nano-vaccine development for leishmaniasis–A review

P Prasanna, P Kumar, S Kumar, VK Rajana… - Biomedicine & …, 2021 - Elsevier
The study of tropical diseases like leishmaniasis, a parasitic disease, has not received much
attention even though it is the second-largest infectious disease after malaria. As per the …

Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery

JC Sunshine, MI Akanda, D Li, KL Kozielski… - …, 2011 - ACS Publications
A new 320-member polymer library of end-modified poly (β-amino ester) s was synthesized.
This library was chosen such that small differences to the structures of component …

Nanopharmaceuticals as a solution to neglected diseases: Is it possible?

GA Islan, M Durán, ML Cacicedo, G Nakazato… - Acta tropica, 2017 - Elsevier
The study of neglected diseases has not received much attention, especially from public and
private institutions over the last years, in terms of strong support for developing treatment for …

Polymer nanotechnology based approaches in mucosal vaccine delivery: challenges and opportunities

R Sharma, U Agrawal, N Mody, SP Vyas - Biotechnology advances, 2015 - Elsevier
Mucosal sites serve as the main portal for the entry of pathogens and thus immunization
through mucosal routes can greatly improve the immunity. Researchers are continuously …