Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Production of 3-hydroxypropanoic acid from glycerol by metabolically engineered bacteria

C Jers, A Kalantari, A Garg, I Mijakovic - Frontiers in Bioengineering …, 2019 - frontiersin.org
3-hydroxypropanoic acid (3-HP) is a valuable platform chemical with a high demand in the
global market. 3-HP can be produced from various renewable resources. It is used as a …

Multilayer Engineering of an Escherichia coli-Based Biotransformation System to Exclusively Produce Glycolic Acid from Formaldehyde

HJ Jo, H Yu, H Cheon, JH Kim, GY Kim… - ACS Sustainable …, 2023 - ACS Publications
A whole-cell biocatalysis was investigated for the selective synthesis of the industrially
relevant C2 chemicals (eg, glycolic acid (3)) from formaldehyde (1). Escherichia coli cells …

Directed evolution of the 3-hydroxypropionic acid production pathway by engineering aldehyde dehydrogenase using a synthetic selection device

JY Seok, J Yang, SJ Choi, HG Lim, UJ Choi, KJ Kim… - Metabolic …, 2018 - Elsevier
Hydroxypropionic acid (3-HP) is an important platform chemical, and biological production of
3-HP from glycerol as a carbon source using glycerol dehydratase (GDHt) and aldehyde …

Biotransformation of ethylene glycol to glycolic acid by Yarrowia lipolytica: A route for poly(ethylene terephthalate) (PET) upcycling

A Carniel, AG Santos, LS Chinelatto… - Biotechnology …, 2023 - Wiley Online Library
Biological recycling of PET waste has been extensively investigated recently to tackle plastic
waste pollution, and ethylene glycol (EG) is one of the main building blocks recovered from …

Exploiting tandem repetitive promoters for high-level production of 3-hydroxypropionic acid

P Zhao, C Ma, L Xu, P Tian - Applied microbiology and biotechnology, 2019 - Springer
High-level biosynthesis of desired metabolites is challenging due to complexity of metabolic
networks. Here, we report that platform chemical 3-hydroxypropionic acid (3-HP) can be …

Heterologous production of acrylic acid: Current challenges and perspectives

JL Rodrigues - SynBio, 2022 - mdpi.com
Acrylic acid (AA) is a chemical with high market value used in industry to produce diapers,
paints, adhesives and coatings, among others. AA available worldwide is chemically …

Development of Pseudomonas asiatica as a host for the production of 3-hydroxypropionic acid from glycerol

TT Nguyen, S Lama, SK Ainala… - Bioresource …, 2021 - Elsevier
Pseudomonas asiatica C1, which could grow on glucose and aerobically synthesize
coenzyme B 12, was isolated and developed as a microbial cell factory for the production of …

Glycerol as a key reactant in the production of 3-hydroxypropanoic acid using engineered microbes

P Jeevitha, KS Elango, G Babu L, J Ranjitha… - AIP Conference …, 2021 - pubs.aip.org
In this paper, we have described the production of 3-Hydroxypropanoic acid using glycerol
as a key intermediate in the presence of engineered microbes. 3-hydroxypropanoic acid (3 …

Synthetic translational coupling system for accurate and predictable polycistronic gene expression control in bacteria

YH Han, HJ Kim, K Kim, J Yang, SW Seo - Metabolic Engineering, 2024 - Elsevier
Precise and predictable genetic elements are required to address various issues, such as
suboptimal metabolic flux or imbalanced protein assembly caused by the inadequate control …