Abstract c-Jun N-terminal kinase (JNK) signalling regulates both cancer cell apoptosis and
survival. Emerging evidence show that JNK promoted tumour progression is involved in …

Lung cancer is one of the most common cancers in the population and is characterized by
non-specific symptoms that delay the diagnosis and reduce the effectiveness of oncological …

Mitogen-activated protein kinases (MAP kinases) are a family of kinases that regulates a
range of biological processes implicated in the response to growth factors like latelet …

Purpose: The effects of Rho-associated coiled-coil containing protein kinase (ROCK) 1 and
2 inhibitor, ripasudil hydrochloride hydrate (Rip), ROCK2 inhibitor, KD025 or rosiglitazone …

The JNKs are members of mitogen-activated protein kinases (MAPK) which regulate many
physiological processes including inflammatory responses, macrophages, cell proliferation …

Immune abnormality involves in various diseases, such as infection, allergic diseases,
autoimmune diseases, as well as transplantation. Several signal pathways have been …

Metallothioneins (MTs), low molecular mass cysteine-rich proteins, which are able to bind up
to 20 monovalent and up to 7 divalent heavy metal ions are widely studied due to their …

Abstract M3 muscarinic receptors (M3R) modulate β-catenin signaling and colon neoplasia.
CDC42/RAC guanine nucleotide exchange factor, βPix, binds to β-catenin in colon cancer …

Although substantial studies on peroxisome proliferator-activated receptor γ (PPARγ) have
focused on the mechanisms by which PPARγ regulates glucose and lipid metabolism …

Objective To study the role of m6A and lncRNAs in the prognosis and immunotherapy of
hepatocellular carcinoma, construct the risk score of overall survival of hepatocellular …