Genomic and proteomic insights into the heavy metal bioremediation by cyanobacteria

H Chakdar, S Thapa, A Srivastava, P Shukla - Journal of Hazardous …, 2022 - Elsevier
Heavy metals (HMs) pose a global ecological threat due to their toxic effects on aquatic and
terrestrial life. Effective remediation of HMs from the environment can help to restore soil's …

Recent progress in the synthesis of advanced biofuel and bioproducts

BF Pfleger, R Takors - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights●Why biofuels and bioproducts remain critical to society●What molecular
products can be made by biotechnology using available feedstocks●How new systems and …

A critical review of genome editing and synthetic biology applications in metabolic engineering of microalgae and cyanobacteria

IS Ng, BB Keskin, SI Tan - Biotechnology Journal, 2020 - Wiley Online Library
Being the green gold of the future, microalgae and cyanobacteria have recently attracted
considerable interest worldwide, for their metabolites such as lipids, protein, pigments, and …

Deciphering and engineering photosynthetic cyanobacteria for heavy metal bioremediation

J Cui, Y Xie, T Sun, L Chen, W Zhang - Science of The Total Environment, 2021 - Elsevier
Environmental pollution caused by heavy metals has received worldwide attentions due to
their ubiquity, poor degradability and easy bioaccumulation in host cells. As one potential …

Design of synthetic promoters for cyanobacteria with generative deep-learning model

E Seo, YN Choi, YR Shin, D Kim… - Nucleic Acids …, 2023 - academic.oup.com
Deep generative models, which can approximate complex data distribution from large
datasets, are widely used in biological dataset analysis. In particular, they can identify and …

SEVA-Cpf1, a CRISPR-Cas12a vector for genome editing in cyanobacteria

S Baldanta, G Guevara, JM Navarro-Llorens - Microbial cell factories, 2022 - Springer
Background Cyanobacteria are photosynthetic autotrophs that have tremendous potential
for fundamental research and industrial applications due to their high metabolic plasticity …

Potential use of microbial engineering in single-cell protein production

B Balagurunathan, H Ling, WJ Choi… - Current opinion in …, 2022 - Elsevier
Highlights•SynBio and genomic engineering enable effective and rapid microbial
engineering.•Microbial engineering can play a significant role in advancing SCP …

Generation of synthetic shuttle vectors enabling modular genetic engineering of cyanobacteria

F Opel, NA Siebert, S Klatt, A Tüllinghoff… - ACS synthetic …, 2022 - ACS Publications
Cyanobacteria have raised great interest in biotechnology due to their potential for a
sustainable, photosynthesis-driven production of fuels and value-added chemicals. This has …

Progress and challenges in engineering cyanobacteria as chassis for light‐driven biotechnology

A Hitchcock, CN Hunter, DP Canniffe - Microbial biotechnology, 2020 - Wiley Online Library
Cyanobacteria are prokaryotic phototrophs that, in addition to being excellent model
organisms for studying photosynthesis, have tremendous potential for light‐driven synthetic …

Degradation of antibiotic resistance genes by VADER with CRISPR-Cas immunity

X Li, N Bao, Z Yan, XZ Yuan, SG Wang… - Applied and …, 2023 - Am Soc Microbiol
The evolution and dissemination of antibiotic resistance genes (ARGs) are prompting severe
health and environmental issues. While environmental processes, eg, biological wastewater …