Lithium has been and continues to be the mainstay of bipolar disorder (BD)
pharmacotherapy for acute mood episodes, switch prevention, prophylactic treatment, and …

The prognosis of patients with glioblastoma, anaplastic astrocytoma, and anaplastic
oligodendroglioma remains poor despite standard treatment with radiotherapy and …

PKC isoforms t, α, and β play fundamental roles in the activation of T cells and other immune
cell functions. Here we show that the PKC inhibitor AEB071 both abolishes the production of …

Bipolar disorder is one of the most severely debilitating of all medical illnesses. For a large
number of patients, outcomes are quite poor. The illness results in tremendous suffering for …

More than 100 arboviruses, almost all of which have an RNA genome, cause disease in
humans. RNA viruses are causing unprecedented health system challenges worldwide …

A pharmaceutical grade extract of Coix lachryma-jobi seeds is currently the most commonly
used treatment for cancer in China. Although clinical data supports the use of this …

Epstein-Barr virus (EBV) is a widespread human herpes virus associated with lymphomas
and epithelial cell cancers. It establishes two separate infection phases, latent and lytic, in …

Natural products are characterized by extreme structural diversity and thus they offer a
unique source for the identification of novel anti-tumor agents. Herein, we report that the …

Abstract Background Arsenic trioxide (As 2 O 3) exhibits promising anticarcinogenic activity
in acute promyelocytic leukemic patients and induces apoptosis in various tumor cells in …

Multiple myeloma is a plasma cell neoplasm with a median survival of 3 to 5 years. Recent
advances have improved patient outlook, but the disease remains incurable. Therefore …