Neisseria meningitidis: using genomics to understand diversity, evolution and pathogenesis

DA Caugant, OB Brynildsrud - Nature Reviews Microbiology, 2020 - nature.com
Meningococcal disease remains an important cause of morbidity and death worldwide
despite the development and increasing implementation of effective vaccines. Elimination of …

Emerging facets of prokaryotic glycosylation

C Schäffer, P Messner - FEMS microbiology reviews, 2017 - academic.oup.com
Glycosylation of proteins is one of the most prevalent post-translational modifications
occurring in nature, with a wide repertoire of biological implications. Pathways for the main …

The sweet tooth of bacteria: common themes in bacterial glycoconjugates

HLP Tytgat, S Lebeer - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Humans have been increasingly recognized as being superorganisms, living in close
contact with a microbiota on all their mucosal surfaces. However, most studies on the human …

Sugar coating: bacterial protein glycosylation and host–microbe interactions

FYY Tan, CM Tang, RM Exley - Trends in biochemical sciences, 2015 - cell.com
Bacterial surfaces are rich in glycoconjugates such as capsules, lipopolysaccharides, and
peptidoglycans. The discovery of prokaryotic protein glycosylation systems has revealed that …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2009–2010

DJ Harvey - Mass spectrometry reviews, 2015 - Wiley Online Library
This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

Acinetobacter strains carry two functional oligosaccharyltransferases, one devoted exclusively to type IV pilin, and the other one dedicated to O‐glycosylation of …

CM Harding, MA Nasr, RL Kinsella… - Molecular …, 2015 - Wiley Online Library
Multiple species within the A cinetobacter genus are nosocomial opportunistic pathogens of
increasing relevance worldwide. Among the virulence factors utilized by these bacteria are …

Defining early steps in Bacillus subtilis biofilm biosynthesis

CA Arbour, R Nagar, HM Bernstein, S Ghosh… - Mbio, 2023 - Am Soc Microbiol
The Bacillus subtilis extracellular biofilm matrix includes an exopolysaccharide (EPS) that is
critical for the architecture and function of the community. To date, our understanding of the …

Diversity in the protein N-glycosylation pathways within the Campylobacter genus

H Nothaft, NE Scott, E Vinogradov, X Liu, R Hu… - Molecular & Cellular …, 2012 - ASBMB
The foodborne bacterial pathogen, Campylobacter jejuni, possesses an N-linked protein
glycosylation (pgl) pathway involved in adding conserved heptasaccharides to asparagine …

Diversity within the O-linked protein glycosylation systems of Acinetobacter species

NE Scott, RL Kinsella, AVG Edwards, MR Larsen… - Molecular & Cellular …, 2014 - ASBMB
The opportunistic human pathogen Acinetobacter baumannii is a concern to health care
systems worldwide because of its persistence in clinical settings and the growing frequency …

Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

J Gault, M Ferber, S Machata, AF Imhaus… - PLoS …, 2015 - journals.plos.org
The ability of pathogens to cause disease depends on their aptitude to escape the immune
system. Type IV pili are extracellular filamentous virulence factors composed of pilin …