The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

The prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million
people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is …

MicroRNAs (miRNAs) are small non-coding RNAs of∼ 22 nucleotides, which have
increasingly been recognized as potent post-transcriptional regulators of gene expression …

Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly
of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is …

Vascular remodelling is a multifactorial process that involves both adaptive and maladaptive
changes of the vessel wall through, among others, cell proliferation and migration, but also …

Critical limb ischemia (CLI) constitutes the most severe form of peripheral arterial disease
(PAD), it is characterized by progressive blockade of arterial vessels, commonly correlated …

Accumulating evidence indicates that microRNAs (miRs)—non‐coding RNAs that can
regulate gene expression via translational repression and/or post‐transcriptional …

Non-coding RNAs are functional RNA molecules comprising the majority of human
transcriptome. Only about 1.5% of the human genome is transcribed into messenger RNAs …

MicroRNAs are posttranscriptional regulators of gene expression. As microRNAs can target
many genes simultaneously, microRNAs can regulate complex multifactorial processes …

Background: Mesenchymal stem cells (MSCs) secrete trophic factors and extracellular
vesicles (EVs). However, the level and role of EVs after MSC therapy in patients with stroke …