The COVID-19 pandemic has necessitated the development of reliable diagnostic methods
for accurately detecting the novel coronavirus and its variants. Deep learning (DL) …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hybrid immunity is more
protective than vaccination or previous infection alone. To investigate the kinetics of spike …

Introduction Many people with long COVID symptoms suffer from debilitating neurologic post-
acute sequelae of SARS-CoV-2 infection (Neuro-PASC). Although symptoms of Neuro …

T cells targeting self-proteins are important mediators in autoimmune diseases. T cells
express unique cell-surface receptors (TCRs) that recognize peptides presented by major …

The development of systems biology represents an immense breakthrough in our ability to
perform translational research and deliver personalized and precision medicine. A …

The anti-spike T-cell and antibody responses to SARS-CoV-2 mRNA vaccines in patients
with B-cell malignancies were examined in a real-world setting. A next-generation …

Obesity is a known risk factor for severe respiratory tract infections. In this prospective study,
we assessed the impact of being obese or overweight on longitudinal SARS-CoV-2 humoral …

SARS-CoV-2 provokes a robust T cell response. Peptide-based studies exclude antigen
processing and presentation biology, which may influence T cell detection studies. To focus …

Objectives Elderly are an understudied, high-risk group vulnerable to severe COVID-19. We
comprehensively analyzed the durability of humoral and cellular immune responses after …

T-cell–based diagnostic tools identify pathogen exposure but lack differentiation between
recent and historical exposures in acute infectious diseases. Here, T-cell receptor (TCR) …