In vivo confocal microscopy of corneal nerves in health and disease

A Cruzat, Y Qazi, P Hamrah - The ocular surface, 2017 - Elsevier
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

[HTML][HTML] A systematic review on the impact of diabetes mellitus on the ocular surface

K Shih, KSL Lam, L Tong - Nutrition & diabetes, 2017 - nature.com
Diabetes mellitus is associated with extensive morbidity and mortality in any human
community. It is well understood that the burden of diabetes is attributed to chronic …

[HTML][HTML] Rapid automated diagnosis of diabetic peripheral neuropathy with in vivo corneal confocal microscopy

IN Petropoulos, U Alam, H Fadavi… - … & visual science, 2014 - tvst.arvojournals.org
Purpose.: To assess the diagnostic validity of a fully automated image analysis algorithm of
in vivo confocal microscopy images in quantifying corneal subbasal nerves to diagnose …

Ocular complications of diabetes and therapeutic approaches

VJ Vieira-Potter, D Karamichos… - BioMed research …, 2016 - Wiley Online Library
Diabetes mellitus (DM) is a metabolic disease defined by elevated blood glucose (BG). DM
is a global epidemic and the prevalence is anticipated to continue to increase. The ocular …

In Vivo Confocal Microscopy of the Ocular Surface: From Bench to Bedside

E Villani, C Baudouin, N Efron, P Hamrah… - Current eye …, 2014 - Taylor & Francis
In vivo confocal microscopy (IVCM) is an emerging technology that provides minimally
invasive, high resolution, steady-state assessment of the ocular surface at the cellular level …

Corneal nerve loss detected with corneal confocal microscopy is symmetrical and related to the severity of diabetic polyneuropathy

IN Petropoulos, U Alam, H Fadavi, O Asghar… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE To establish if corneal nerve loss, detected using in vivo corneal confocal
microscopy (IVCCM), is symmetrical between right and left eyes and relates to the severity of …

Corneal confocal microscopy: ready for prime time

IN Petropoulos, G Ponirakis, A Khan… - Clinical and …, 2020 - Taylor & Francis
Corneal confocal microscopy is a non‐invasive ophthalmic imaging modality, which was
initially used for the diagnosis and management of corneal diseases. However, over the last …

[HTML][HTML] Greater corneal nerve loss at the inferior whorl is related to the presence of diabetic neuropathy and painful diabetic neuropathy

A Kalteniece, M Ferdousi, I Petropoulos, S Azmi… - Scientific reports, 2018 - nature.com
We assessed whether a measure of more distal corneal nerve fibre loss at the inferior whorl
(IW) region is better than proximal measures of central corneal nerve damage in relation to …

Structural and functional changes in corneal innervation after laser in situ keratomileusis and their relationship with dry eye

C Chao, F Stapleton, X Zhou, S Chen, S Zhou… - Graefe's Archive for …, 2015 - Springer
Purpose The most likely etiology of post-LASIK dry eye is corneal nerve damage; however,
no direct relationship between post-LASIK dry eye symptoms and nerve damage has been …

[HTML][HTML] The inferior whorl for detecting diabetic peripheral neuropathy using corneal confocal microscopy

IN Petropoulos, M Ferdousi, A Marshall… - … & visual science, 2015 - iovs.arvojournals.org
Purpose.: In vivo corneal confocal microscopy (CCM) is increasingly used as a surrogate
endpoint in studies of diabetic polyneuropathy (DPN). However, it is not clear whether …