Background Diagnostic approaches like the nuclear magnetic resonance spectroscopy
(NMR) based quantification of metabolites, lipoproteins, and inflammation markers has …

Numerous studies have shown that a low level of high-density lipoprotein cholesterol (HDL-
C) is an independent biomarker of cardiovascular disease. High-density lipoprotein (HDL) is …

Type 2 diabetes mellitus (T2DM) is a major global public health problem, as it is associated
with increased morbidity, mortality, and healthcare costs. Insulin resistance (IR) is a …

The relationship between pesticide exposures and metabolomics biomarkers is not well
understood. We examined the changes in the serum metabolome (early biomarkers) and the …

Inflammation, oxidative stress, and mitochondrial function are implicated in the development
of obesity and its comorbidities. The purpose of this study was to assess the impact of weight …

HDL-cholesterol quality, including cholesterol distribution in HDL subfractions, is emerging
as a key discriminant in dictating the effects of these lipoproteins on cardiovascular health …

Cholesteryl ester transfer protein (CETP) is known to influence HDL-C levels, potentially
altering the profile of HDL subfractions and consequently cardiovascular risk (CVR). This …

Glucagon-like peptide-1 receptor agonist (GLP-1RA) has been clinically proven to protect
endothelial function. Previously, we demonstrated that endothelial NO synthase (eNOS) was …

Background The exact pathophysiology of humans suffering from the multifaceted SARS-
CoV-2 infection is not yet conclusively understood and risk stratification is needed. Novel …

La variabilité de la réponse aux médicaments entre les individus est en grande partie
attribuable aux différences génétiques causées par des mutations génétiques. Ces …