Interaction of SARS-CoV-2 with host cells and antibodies: experiment and simulation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
COVID-19 in the 47 countries of the WHO African region: a modelling analysis of past trends and future patterns
JW Cabore, HC Karamagi, HK Kipruto… - The lancet global …, 2022 - thelancet.com
Background COVID-19 has affected the African region in many ways. We aimed to generate
robust information on the transmission dynamics of COVID-19 in this region since the …
robust information on the transmission dynamics of COVID-19 in this region since the …
Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants
The omicron variants of SARS-CoV-2 have substantial ability to escape infection-and
vaccine-elicited antibody immunity. Here, we investigated the extent of such escape in nine …
vaccine-elicited antibody immunity. Here, we investigated the extent of such escape in nine …
Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain
The Omicron variant features enhanced transmissibility and antibody escape. Here, we
describe the Omicron receptor-binding domain (RBD) mutational landscape using amino …
describe the Omicron receptor-binding domain (RBD) mutational landscape using amino …
[HTML][HTML] Insights on the mutational landscape of the SARS-CoV-2 Omicron variant
Abstract The SARS-COV2 Omicron variant has sparked global concern due to the possibility
of enhanced transmissibility and escape from vaccines and therapeutics. In this study, we …
of enhanced transmissibility and escape from vaccines and therapeutics. In this study, we …
Omicron BQ. 1.1 and XBB. 1 unprecedentedly escape broadly neutralizing antibodies elicited by prototype vaccination
B Ju, Q Fan, C Liu, S Shen, M Wang, H Guo, B Zhou… - Cell Reports, 2023 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants have
seriously attacked the antibody barrier established by natural infection and/or vaccination …
seriously attacked the antibody barrier established by natural infection and/or vaccination …
Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209
Dear Editor, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and its variants is still a pandemic raging across the …
syndrome coronavirus 2 (SARS-CoV-2) and its variants is still a pandemic raging across the …
The D Gene in CDR H3 Determines a Public Class of Human Antibodies to SARS-CoV-2
M Yuan, IA Wilson - Vaccines, 2024 - mdpi.com
Public antibody responses have been found against many infectious agents. Structural
convergence of public antibodies is usually determined by immunoglobulin V genes …
convergence of public antibodies is usually determined by immunoglobulin V genes …
Additional mutations based on Omicron BA. 2.75 mediate its further evasion from broadly neutralizing antibodies
H Guo, J Jiang, S Shen, X Ge, Q Fan, B Zhou, L Cheng… - Iscience, 2023 - cell.com
Summary SARS-CoV-2 Omicron BA. 2.75 subvariant has evolved to a series of progeny
variants carrying several additional mutations in the receptor-binding domain (RBD). Here …
variants carrying several additional mutations in the receptor-binding domain (RBD). Here …
[HTML][HTML] Increased resistance of SARS-CoV-2 Lambda variant to antibody neutralization
H Guo, Q Fan, S Song, S Shen, B Zhou, H Wang… - Journal of Clinical …, 2022 - Elsevier
A recently identified SARS-CoV-2 variant, Lambda, has spread to many countries around
the world. Here, we measured and evaluated the reduced sensitivity of Lambda variant to …
the world. Here, we measured and evaluated the reduced sensitivity of Lambda variant to …