Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

A major feature of Alzheimer's disease (AD) pathology is the plaque composed of
aggregated amyloid-β (Aβ) peptide. Although these plaques may have harmful properties …

Background Cigarette smoking has been linked with both increased and decreased risk for
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …

Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …

Alzheimer's disease (AD) is a neurodegenerative disorder linked to protein misfolding and
aggregation. AD is pathologically characterized by senile plaques formed by extracellular …

Alzheimer's Disease (AD) is the most common form of dementia, affecting almost 50 million
of people around the world, characterized by a complex and age-related progressive …

Alzheimer's disease (AD) is a fatal progressive neurodegenerative disorder characterized by
increasing loss in memory, cognition, and function of daily living. Among the many …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects more than
24 million people worldwide and represents an immense medical, social and economic …

The aging population increases steadily because of a healthy lifestyle and medical
advancements in healthcare. However, Alzheimer's disease (AD) is becoming more …

The cholinergic system plays an essential role in brain development, physiology, and
pathophysiology. Herein, we review how specific alterations in this system, through genetic …