Oncolytic viruses for triple negative breast cancer and beyond

S Jin, Q Wang, H Wu, D Pang, S Xu - Biomarker Research, 2021 - Springer
Biological therapy is considered an alternative treatment capable of eliciting the same
effects on tumors as surgery, radiotherapy, and chemotherapy. As a major player in …

Pathogenetic features and current management of glioblastoma

HM Nguyen, K Guz-Montgomery, DB Lowe, D Saha - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most common form of primary malignant brain
tumor with a devastatingly poor prognosis. Tumor heterogeneity (cellular, molecular and …

[HTML][HTML] Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma

D Saha, SD Rabkin, RL Martuza - Journal for ImmunoTherapy of …, 2020 - ncbi.nlm.nih.gov
Background Temozolomide (TMZ) chemotherapy is a current standard of care for
glioblastoma (GBM), however it has only extended overall survival by a few months …

Clinical trials of oncolytic viruses in breast cancer

ME Carter, A Koch, UM Lauer, AD Hartkopf - Frontiers in oncology, 2021 - frontiersin.org
Breast cancer is the second most common kind of cancer worldwide and oncolytic viruses
may offer a new treatment approach. There are three different types of oncolytic viruses used …

Oncolytic virotherapy for breast cancer treatment

SM O'Bryan, JM Mathis - Current Gene Therapy, 2018 - ingentaconnect.com
Breast cancer continues to be a leading cause of mortality among women. While at an early
stage, localized breast cancer is easily treated; however, advanced stages of disease …

Triple-negative breast cancer: basic biology and immuno-oncolytic viruses

ML Monaco, OA Idris, K Essani - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is an aggressive as well as the most
dangerous form of breast cancer. Due to the lack of biomarkers that can be targeted by …

[HTML][HTML] Oncolytic viruses: A novel treatment strategy for breast cancer

M Javanbakht, S Tahmasebzadeh, L Cegolon… - Genes & …, 2023 - Elsevier
Breast cancer, an unceasingly occurring neoplasm, is one of the major determinants of
mortality in women. Several ineffective attempts have been pursued using with conventional …

Targeting palbociclib-resistant estrogen receptor-positive breast cancer cells via oncolytic virotherapy

N Lypova, L Lanceta, A Gipson, S Vega… - Cancers, 2019 - mdpi.com
While clinical responses to palbociclib have been promising, metastatic breast cancer
remains incurable due to the development of resistance. We generated estrogen receptor …

[PDF][PDF] Recombinant oncolytic adenovirus combined with cyclophosphamide induces synergy in the treatment of breast cancer in vitro and in vivo

J Wang, S Zuo, Y Zhang, S Li, Y Shi, T Du… - Cancer management …, 2022 - Taylor & Francis
Purpose Oncolytic virus therapy has gradually become an integral approach in cancer
treatment. We explored the therapeutic effects of the combination of a dual cancer-selective …

Viral therapy for targeted drug delivery to cancers: Recent advances, clinical and regulatory perspectives

K Dhuri, S Gharat, N Fernandes, V Basudkar… - Journal of Drug Delivery …, 2024 - Elsevier
Virotherapy is a potential anticancer therapy that uses viral agents to locate and destroy
cancerous cells. Clinical trials conducted on viruses, both naturally oncolytic and those …