The myc family and the metastasis suppressor NDRG1: targeting key molecular interactions with innovative therapeutics
Z Deng, DR Richardson - Pharmacological Reviews, 2023 - ASPET
Cancer is a leading cause of death worldwide, resulting in∼ 10 million deaths in 2020.
Major oncogenic effectors are the Myc proto-oncogene family, which consists of three …
Major oncogenic effectors are the Myc proto-oncogene family, which consists of three …
Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy
BA Fang, Ž Kovačević, KC Park, DS Kalinowski… - … et Biophysica Acta (BBA …, 2014 - Elsevier
N-myc down-regulated gene 1 (NDRG1) is a known metastasis suppressor in multiple
cancers, being also involved in embryogenesis and development, cell growth and …
cancers, being also involved in embryogenesis and development, cell growth and …
ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction
The serine synthesis pathway (SSP) involving metabolic enzymes phosphoglycerate
dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine …
dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine …
Novel lncRNA LINC00844 Regulates Prostate Cancer Cell Migration and Invasion through AR Signaling
S Lingadahalli, S Jadhao, YY Sung, M Chen… - Molecular Cancer …, 2018 - AACR
The human genome is mostly transcribed, yielding a rich repository of noncoding transcripts
that are involved in a myriad of biological processes including cancer. However, how many …
that are involved in a myriad of biological processes including cancer. However, how many …
[PDF][PDF] The role of cancer stem cells in relapse of solid tumors
[Frontiers in Bioscience E4, 1528-1541, January 1, 2012] 1528 The role of cancer stem cells in
relapse of solid tumors Yang Yu1 Page 1 [Frontiers in Bioscience E4, 1528-1541, January 1 …
relapse of solid tumors Yang Yu1 Page 1 [Frontiers in Bioscience E4, 1528-1541, January 1 …
Exosomal tetraspanins as regulators of cancer progression and metastasis and novel diagnostic markers
RR Malla, S Pandrangi, S Kumari… - Asia‐Pacific Journal …, 2018 - Wiley Online Library
Exosomes are cell–cell communicators emerging as a new paradigm for noninvasive
diagnosis and prognosis of treatment response. Exosomal tetraspanin proteins like CD63 …
diagnosis and prognosis of treatment response. Exosomal tetraspanin proteins like CD63 …
The role of the NDRG1 in the pathogenesis and treatment of breast cancer
X Zhao, DR Richardson - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Breast cancer (BC) is the leading cause of cancer death in women. This disease is
heterogeneous, with clinical subtypes being estrogen receptor-α (ER-α) positive, having …
heterogeneous, with clinical subtypes being estrogen receptor-α (ER-α) positive, having …
Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors
The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), is negatively
correlated with tumor progression in multiple neoplasms, being a promising new target for …
correlated with tumor progression in multiple neoplasms, being a promising new target for …
The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer …
L Mi, F Zhu, X Yang, J Lu, Y Zheng, Q Zhao, X Wen… - Oncogene, 2017 - nature.com
N-myc downstream-regulated gene 1 (NDRG1) has been reported to act as a key regulatory
molecule in tumor progression-related signaling pathways, especially in tumor metastasis …
molecule in tumor progression-related signaling pathways, especially in tumor metastasis …
The role of NDRG1 in the pathology and potential treatment of human cancers
DH Bae, PJ Jansson, ML Huang, Z Kovacevic… - Journal of clinical …, 2013 - jcp.bmj.com
N-myc downstream regulated gene 1 (NDRG1) has been well characterised to act as a
metastatic suppressor in a number of human cancers. It has also been implicated to have a …
metastatic suppressor in a number of human cancers. It has also been implicated to have a …