Since the 1970s, introduction of serological assays targeting virus-specific antibodies and
antigens has been effective in identifying blood donations infected with the classic …

German Advisory Committee Blood (Arbeitskreis Blut), Subgroup 'Assessment of Pathogens
Transmissible by Blood'tein, TM) are derived. In addition to the structural proteins, the HIV …

Hepatitis B virus (HBV) remains a major public health problem worldwide, despite the
availability of an effective vaccine and antiviral therapies. More than 240 million people …

Nowadays patients receiving blood components are exposed to much less transfusion-
transmitted infectious diseases than three decades before when among others HIV was …

Over the past decades, the risk of HBV transfusion–transmission has been steadily reduced
through the recruitment of volunteer donors, the selection of donors based on risk-behavior …

Numerous cell-based therapeutics are currently being tested in clinical trials. Human platelet
lysate (HPL) is a valuable alternative to fetal bovine serum as a cell culture medium …

Background Twelve percent of all acute liver failure (ALF) cases are of unknown origin, often
termed indeterminate. A previously unrecognized hepatotropic virus has been suspected as …

Nucleic acid testing (NAT) is a molecular technique for screening blood donations to reduce
the risk of transfusion transmitted infections (TTIs) in the recipients, thus providing an …

Abstract The Asian Pacific Association for the Study of the Liver (APASL) convened an
international working party on “APASL consensus statements and recommendations for …

Background Hepatitis B virus (HBV) DNA‐positive yield since nucleic acid testing (NAT)
implementation (minipools of 16 [MP 16]) was reported for the first year. We have updated …