Male reproductive development is intricately dependent on fetal androgen action.
Consequently, disrupted androgen action during fetal life can interfere with the development …

Abnormal foetal testis development has been proposed to underlie common disorders of the
male reproductive system such as cryptorchidism, hypospadias, reduced semen quality and …

STUDY QUESTION Is first trimester phthalate exposure associated with anogenital distance
(AGD), a biomarker of prenatal androgen exposure, in newborns? SUMMARY ANSWER …

Background: Phthalates are used as plasticizers in soft polyvinyl chloride (PVC) and in a
large number of consumer products. Because of reported health risks, diisononyl phthalate …

Context: Male reproductive disorders evident at birth or in young adulthood are remarkably
common. They are hypothesized to comprise a testicular dysgenesis syndrome (TDS), with a …

Human male reproductive disorders are common and may have a fetal origin—the testicular
dysgenesis syndrome (TDS) hypothesis. In rats, experimentally induced TDS disorders …

Paracetamol and NSAIDs, in particular acetylsalicylic acid (aspirin) and ibuprofen, are
among the most used and environmentally released pharmaceutical drugs. The differences …

For years, scientists from various disciplines have studied the effects of endocrine disrupting
chemicals (EDCs) on the health and wellbeing of humans and wildlife. Some studies have …

The testicular dysgenesis syndrome (TDS) hypothesis, which proposes that common
reproductive disorders of newborn and adult human males may have a common fetal origin …

We provide an in-depth review of the role of androgens in male maturation and
development, from the fetal stage through adolescence into emerging adulthood, and …