Abstract BCR:: ABL1-negative myeloproliferative neoplasms (MPNs) are clonal diseases
originating from a single hematopoietic stem cell that cause excessive production of mature …

Polycythemia vera (PV) and essential thrombocythemia (ET) constitute two of the three BCR-
ABL1-negative myeloproliferative neoplasms and are characterized by relatively long …

The classic Philadelphia chromosome–negative myeloproliferative neoplasms (MPN)
consist of myelofibrosis, polycythemia vera, and essential thrombocythemia and are a …

The identification of JAK2/MPL mutations in patients with myeloproliferative neoplasms
(MPN) has led to the clinical development of JAK kinase inhibitors, including ruxolitinib …

Abstract Objective To document the Mayo Clinic decades-long experience with
myeloproliferative neoplasms (MPNs) and provide mature risk-stratified survival data and …

1Guy's and St Thomas' NHS Foundation Trust, London, 2Russells Hall Hospital, Dudley,
West Midlands, 3Arrowe Park Hospital Arrowe Park Road Upton Wirral, 4Wellcome Trust …

Leukemic transformation in myeloproliferative neoplasms (MPN), also referred to as “blast-
phase MPN”, is the most feared disease complication, with incidence estimates of 1–4% for …

Secondary acute myeloid leukemias (AMLs) evolving from an antecedent myeloproliferative
neoplasm (MPN) are characterized by a unique set of cytogenetic and molecular features …

A total of 410 patients with blast phase myeloproliferative neoplasm (MPN-BP) were
retrospectively reviewed: 248 from the Mayo Clinic and 162 from Italy. Median survival was …

Abstract According to the 2008 World Health Organization classification system for
hematologic malignancies, the myeloproliferative neoplasms (MPN) include chronic …