Diffusion MRI has provided the neuroimaging community with a powerful tool to acquire in-
vivo data sensitive to microstructural features of white matter, up to 3 orders of magnitude …

Diffusion MRI‐based tractography is the most commonly‐used technique when inferring the
structural brain connectome, ie, the comprehensive map of the connections in the brain. The …

Alzheimer's disease is increasingly considered a large-scale network disconnection
syndrome, associated with progressive aggregation of pathological proteins, cortical …

Objective As gene-based therapies may soon arise for patients with spinocerebellar ataxia
(SCA), there is a critical need to identify biomarkers of disease progression with effect sizes …

Objective Although temporal lobe epilepsy (TLE) is recognized as a system‐level disorder,
little work has investigated pathoconnectomics from a dynamic perspective. By leveraging …

Long term irreversible disability in multiple sclerosis (MS) is thought to be primarily driven by
axonal degeneration. Axonal degeneration leads to degenerative atrophy, therefore early …

Growing evidence highlights the importance of white matter in the pathogenesis of focal
epilepsy. Ex vivo and post-mortem studies show pathological changes in epileptic patients …

Objective Recent work has shown that people with common epilepsies have characteristic
patterns of cortical thinning, and that these changes may be progressive over time …

Objective The purpose of this study was to evaluate the relation between cognitive
performance and white matter (WM) integrity in patients with temporal lobe epilepsy (TLE) …

Objective The dominant model of cognitive impairment in focal epilepsy has emphasised
structural bases for cognitive deficits. Current theories of cognition in the healthy brain …