The quest to slow ageing through drug discovery
L Partridge, M Fuentealba, BK Kennedy - Nature Reviews Drug …, 2020 - nature.com
Although death is inevitable, individuals have long sought to alter the course of the ageing
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
process. Indeed, ageing has proved to be modifiable; by intervening in biological systems …
Multifarious beneficial effect of nonessential amino acid, glycine: a review
MA Razak, PS Begum, B Viswanath… - … medicine and cellular …, 2017 - Wiley Online Library
Glycine is most important and simple, nonessential amino acid in humans, animals, and
many mammals. Generally, glycine is synthesized from choline, serine, hydroxyproline, and …
many mammals. Generally, glycine is synthesized from choline, serine, hydroxyproline, and …
Inflammation, vitamin B6 and related pathways
PM Ueland, A McCann, Ø Midttun, A Ulvik - Molecular aspects of medicine, 2017 - Elsevier
The active form of vitamin B6, pyridoxal 5′-phosphate (PLP), serves as a co-factor in more
than 150 enzymatic reactions. Plasma PLP has consistently been shown to be low in …
than 150 enzymatic reactions. Plasma PLP has consistently been shown to be low in …
Glycine metabolism in animals and humans: implications for nutrition and health
W Wang, Z Wu, Z Dai, Y Yang, J Wang, G Wu - Amino acids, 2013 - Springer
Glycine is a major amino acid in mammals and other animals. It is synthesized from serine,
threonine, choline, and hydroxyproline via inter-organ metabolism involving primarily the …
threonine, choline, and hydroxyproline via inter-organ metabolism involving primarily the …
[图书][B] Amino acids: biochemistry and nutrition
G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …
Amino acids and immune function
A deficiency of dietary protein or amino acids has long been known to impair immune
function and increase the susceptibility of animals and humans to infectious disease …
function and increase the susceptibility of animals and humans to infectious disease …
Uptake of nanopolystyrene particles induces distinct metabolic profiles and toxic effects in Caenorhabditis elegans
Nanoplastics are widely used in modern life, for example, in cosmetics and daily use
products, and are attracting concern due to their potential toxic effects on environments. In …
products, and are attracting concern due to their potential toxic effects on environments. In …
The hepatic microcirculation: mechanistic contributions and therapeutic targets in liver injury and repair
B Vollmar, MD Menger - Physiological reviews, 2009 - journals.physiology.org
The complex functions of the liver in biosynthesis, metabolism, clearance, and host defense
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …
are tightly dependent on an adequate microcirculation. To guarantee hepatic homeostasis …
Electrochemical synthesis of glycine from oxalic acid and nitrate
JE Kim, JH Jang, KM Lee, M Balamurugan… - Angewandte …, 2021 - Wiley Online Library
In manufacturing C− N bond‐containing compounds, it is an important challenge to alternate
the conventional methodologies that utilize reactive substrates, toxic reagents, and organic …
the conventional methodologies that utilize reactive substrates, toxic reagents, and organic …
Functions and signaling pathways of amino acids in intestinal inflammation
F He, C Wu, P Li, N Li, D Zhang, Q Zhu… - BioMed research …, 2018 - Wiley Online Library
Intestine is always exposed to external environment and intestinal microorganism; thus it is
more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as …
more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as …