Gene therapy: Comprehensive overview and therapeutic applications
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …
Next-generation sequencing for confronting virus pandemics
Virus pandemics have happened, are happening and will happen again. In recent decades,
the rate of zoonotic viral spillover into humans has accelerated, mirroring the expansion of …
the rate of zoonotic viral spillover into humans has accelerated, mirroring the expansion of …
The role of hepatitis B virus genome variations in HBV-related HCC: effects on host signaling pathways
Hepatocellular carcinoma (HCC) is a significant global health issue, with a high prevalence
in many regions. There are variations in the etiology of HCC in different regions, but most …
in many regions. There are variations in the etiology of HCC in different regions, but most …
The impact of HBV quasispecies features on immune status in HBsAg+/HBsAb+ patients with HBV genotype C using next-generation sequencing
Y Wang, X Xiao, S Chen, C Huang, J Zhou… - Frontiers in …, 2021 - frontiersin.org
Background This study aimed to explore the molecular mechanism of the coexistence of
hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb) serological …
hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (HBsAb) serological …
Inspecting the ribozyme region of hepatitis delta virus genotype 1: conservation and variability
The hepatitis delta virus (HDV) genome has an autocatalytic region called the ribozyme,
which is essential for viral replication. The aim of this study was to use next-generation …
which is essential for viral replication. The aim of this study was to use next-generation …
Genotyping Hepatitis B virus by Next-Generation Sequencing: Detection of Mixed Infections and Analysis of Sequence Conservation
E Dopico, M Vila, D Tabernero, J Gregori… - International Journal of …, 2024 - mdpi.com
Our aim was to develop an accurate, highly sensitive method for HBV genotype
determination and detection of genotype mixtures. We examined the preS and 5′ end of …
determination and detection of genotype mixtures. We examined the preS and 5′ end of …
Hepatitis B Virus Variants with Multiple Insertions and/or Deletions in the X Open Reading Frame 3′ End: Common Members of Viral Quasispecies in Chronic …
S García-García, A Caballero-Garralda, D Tabernero… - Biomedicines, 2022 - mdpi.com
Deletions in the 3′ end region of the hepatitis B virus (HBV) X open reading frame (HBX)
may affect the core promoter (Cp) and have been frequently associated with hepatocellular …
may affect the core promoter (Cp) and have been frequently associated with hepatocellular …
[PDF][PDF] Next-generation sequencing for confronting virus pandemics. Viruses 2022; 14: 600
Virus pandemics have happened, are happening and will happen again. In recent decades,
the rate of zoonotic viral spillover into humans has accelerated, mirroring the expansion of …
the rate of zoonotic viral spillover into humans has accelerated, mirroring the expansion of …
Comparative Metagenomics to Study the Impact of Soil Salinity on Microbial Diversity in Al-Madinah, KSA
MS Waznah, HM Albasri, HA Albahri - 2023 - researchsquare.com
The chemical properties and fertility of soil are greatly influenced by soil microbes, which are
essential to the biogeochemical cycle. Analyzing the microbial structure of soil is important …
essential to the biogeochemical cycle. Analyzing the microbial structure of soil is important …
Studying Hepatitis B and Hepatitis Delta viruses quasispecies by Next-generation sequencing: Conservation, variability, and interaction
B Pacín Ruiz - 2023 - tdx.cat
The Hepatitis B virus (HBV) affects around 296 million people worldwide. Of them, more than
5% are coinfected with Hepatitis delta virus (HDV), causing the most severe viral hepatitis …
5% are coinfected with Hepatitis delta virus (HDV), causing the most severe viral hepatitis …