[HTML][HTML] HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment

C Eggers, G Arendt, K Hahn, IW Husstedt… - Journal of …, 2017 - Springer
The modern antiretroviral treatment of human immunodeficiency virus (HIV-1) infection has
considerably lowered the incidence of opportunistic infections. With the exception of the …

HIV infection, inflammation, immunosenescence, and aging

SG Deeks - Annual review of medicine, 2011 - annualreviews.org
Although antiretroviral therapy for HIV infection prevents AIDS-related complications and
prolongs life, it does not fully restore health. Long-term treated patients remain at higher than …

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

RK Heaton, DB Clifford, DR Franklin Jr, SP Woods… - Neurology, 2010 - AAN Enterprises
Objectives: This is a cross-sectional, observational study to determine the frequency and
associated features of HIV-associated neurocognitive disorders (HAND) in a large, diverse …

[HTML][HTML] HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

RK Heaton, DR Franklin, RJ Ellis, JA McCutchan… - Journal of …, 2011 - Springer
Combination antiretroviral therapy (CART) has greatly reduced medical morbidity and
mortality with HIV infection, but high rates of HIV-associated neurocognitive disorders …

Role of the immune system in HIV-associated neuroinflammation and neurocognitive implications

S Hong, WA Banks - Brain, behavior, and immunity, 2015 - Elsevier
Individuals living with HIV who are optimally treated with combination antiretroviral therapy
(cART) can now lead an extended life. In spite of this remarkable survival benefit from viral …

Cognitive dysfunction in HIV patients despite long-standing suppression of viremia

S Simioni, M Cavassini, JM Annoni, AR Abraham… - Aids, 2010 - journals.lww.com
Objective: To determine the prevalence of cognitive complaints and HIV-associated
neurocognitive disorders (HANDs) in a cohort of aviremic HIV-positive patients. To evaluate …

Controversies in HIV-associated neurocognitive disorders

S Nightingale, A Winston, S Letendre… - The Lancet …, 2014 - thelancet.com
Cross-sectional studies show that around half of individuals infected with HIV-1 have some
degree of cognitive impairment despite the use of antiretroviral drugs. However, prevalence …

Human immunodeficiency virus‐associated neurocognitive disorders: mind the gap

JC McArthur, J Steiner, N Sacktor, A Nath - Annals of neurology, 2010 - Wiley Online Library
Human immunodeficiency virus (HIV)‐associated neurocognitive disorders (HANDs) remain
among the most common disorders in people infected with HIV, even in an era when potent …

Discordance between cerebral spinal fluid and plasma HIV replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy

A Canestri, FX Lescure, S Jaureguiberry… - Clinical Infectious …, 2010 - academic.oup.com
Objective. We report data on 11 patients with neurological symptoms and human
immunodeficiency virus (HIV) cerebrospinal fluid (CSF) viremia contrasting with suppressed …

[HTML][HTML] Central nervous system complications in HIV disease: HIV-associated neurocognitive disorder

S Letendre - Topics in antiviral medicine, 2011 - ncbi.nlm.nih.gov
HIV-associated neurocognitive disorder (HAND) is the result of neural damage caused by
HIV replication and immune activation. Potent antiretroviral therapy has reduced the …