[HTML][HTML] Endocytosis: the nanoparticle and submicron nanocompounds gateway into the cell

D Manzanares, V Ceña - Pharmaceutics, 2020 - mdpi.com
Nanoparticles (NPs) and submicron particles are increasingly used as carriers for delivering
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …

Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective

SA Ejazi, R Louisthelmy, K Maisel - ACS nano, 2023 - ACS Publications
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …

Trends in advanced oral drug delivery system for curcumin: A systematic review

S Pan-On, P Dilokthornsakul… - Journal of Controlled …, 2022 - Elsevier
Although curcumin is globally recognized for its health benefits, its clinical application has
been restricted by its poor aqueous solubility and stability. To overcome these limitations …

[HTML][HTML] Organ-on-a-chip meets artificial intelligence in drug evaluation

S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

[HTML][HTML] Protein-polysaccharide nanocomplexes as nanocarriers for delivery of curcumin: a comprehensive review on preparation methods and encapsulation …

J Xue, Y Luo - Journal of Future Foods, 2023 - Elsevier
Curcumin, commonly used as a coloring agent as well as food additive, has exhibited great
therapeutic efficacy for development of functional foods. In order to expand its applications in …

Palmitic acid-modified bovine serum albumin nanoparticles target scavenger receptor-A on activated macrophages to treat rheumatoid arthritis

T Gong, T Tan, P Zhang, H Li, C Deng, Y Huang… - Biomaterials, 2020 - Elsevier
Palmitic acid-modified bovine serum albumin (PAB) was synthetized and found to own
remarkable scavenger receptor-A (SR-A) targeting ability in vitro and in vivo, through which …

The Emerging Role of Nanomedicine in the Management of Nonalcoholic Fatty Liver Disease: A State‐of‐the‐Art Review

SA Moosavian, T Sathyapalan… - Bioinorganic …, 2021 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease that can lead to
end‐stage liver disease needing a liver transplant. Many pharmacological approaches are …

Erythrocyte membrane-camouflaged gefitinib/albumin nanoparticles for tumor imaging and targeted therapy against lung cancer

Q Wen, Y Zhang, TA Muluh, K Xiong, BQ Wang… - International Journal of …, 2021 - Elsevier
Conventional chemotherapeutic drugs may cause serious side effects such as hepatotoxicity
and renal toxicity due to lack of targeting, which affects therapy outcome and the prognosis …

Recent advances in curcumin-loaded biomimetic nanomedicines for targeted therapies

F Lei, P Li, T Chen, Q Wang, C Wang, Y Liu… - Journal of Drug Delivery …, 2023 - Elsevier
Curcumin shows excellent anti-inflammatory and anti-tumor activities, but its solubility,
stability, and bioavailability are poor. Nanoparticle delivery systems can be used to enhance …

Research progress on the mechanism of nanoparticles crossing the intestinal epithelial cell membrane

Y He, M Cheng, R Yang, H Li, Z Lu, Y Jin, J Feng, L Tu - Pharmaceutics, 2023 - mdpi.com
Improving the stability of drugs in the gastrointestinal tract and their penetration ability in the
mucosal layer by implementing a nanoparticle delivery strategy is currently a research focus …