Vitamin C: the known and the unknown and Goldilocks

SJ Padayatty, M Levine - Oral diseases, 2016 - Wiley Online Library
Vitamin C (Ascorbic Acid), the antiscorbutic vitamin, cannot be synthesized by humans and
other primates, and has to be obtained from diet. Ascorbic acid is an electron donor and acts …

[PDF][PDF] The role of reactive oxygen and antioxidant species in periodontal tissue destruction.

ILC Chapple, JB Matthews - Periodontology 2000, 2007 - researchgate.net
Periodontitis is a term used to describe an inflammatory process, initiated by the plaque
biofilm, that leads to loss of periodontal attachment to the root surface and adjacent alveolar …

Reactive oxygen species and antioxidants in inflammatory diseases

ILC Chapple - Journal of clinical periodontology, 1997 - Wiley Online Library
This paper aims to review the role of free radical‐induced tissue damage and antioxidant
defence mechanisms in inflammatory diseases that involve pathogenic processes similar to …

Salivary markers of oxidative stress in oral diseases

L Tóthová, N Kamodyova, T Červenka… - Frontiers in cellular and …, 2015 - frontiersin.org
Saliva is an interesting alternative diagnostic body fluid with several specific advantages
over blood. These include non-invasive and easy collection and related possibility to do …

Periodontal Disease Mechanisms: Reactive oxygen species: a potential role in the pathogenesis of periodontal diseases

RJ Waddington, R Moseley, G Embery - Oral diseases, 2000 - Wiley Online Library
The pathological events leading to the destruction of the periodontium during inflammatory
periodontal diseases are likely to represent complex interactions involving an imbalance in …

Speciation of metal drugs, supplements and toxins in media and bodily fluids controls in vitro activities

A Levina, DC Crans, PA Lay - Coordination Chemistry Reviews, 2017 - Elsevier
Studies of metal uptake, metabolism and excretion by single bacterial, yeast, plant and
animal cells is a widespread area of research, yet little is known about the reactivity and …

The antioxidant capacity of saliva

M Battino, MS Ferreiro, I Gallardo… - Journal of Clinical …, 2002 - Wiley Online Library
Background/aims: Saliva, a heterogeneous fluid comprising proteins, glycoproteins,
electrolytes, small organic molecules and compounds transported from the blood, constantly …

Local and systemic total antioxidant capacity in periodontitis and health

GR Brock, CJ Butterworth, JB Matthews… - Journal of clinical …, 2004 - Wiley Online Library
Background: The involvement of reactive oxygen species (ROS) in periodontal pathology is
unclear but will be modulated by in vivo antioxidant defence systems. The aim of this cross …

Oxidative injury and inflammatory periodontal diseases: the challenge of anti-oxidants to free radicals and reactive oxygen species

M Battino, P Bullon, M Wilson… - Critical Reviews in Oral …, 1999 - journals.sagepub.com
In recent years, there has been a tremendous expansion in medical and dental research
concerned with free radicals, reactive oxygen species, and anti-oxidant defense …

Lipid peroxidation levels and total oxidant status in serum, saliva and gingival crevicular fluid in patients with chronic periodontitis

FA Akalιn, E Baltacιoğlu, A Alver… - Journal of clinical …, 2007 - Wiley Online Library
Objectives: Increased levels of reactive oxygen species lead to oxidative stress. Recent data
suggest increased lipid peroxidation (LPO) levels and oxidative stress in periodontitis …