Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames
All species continuously evolve short open reading frames (sORFs) that can be templated
for protein synthesis and may provide raw materials for evolutionary adaptation. We …
for protein synthesis and may provide raw materials for evolutionary adaptation. We …
[PDF][PDF] Mutate and observe: utilizing deep neural networks to investigate the impact of mutations on translation initiation
Motivation The primary regulatory step for protein synthesis is translation initiation, which
makes it one of the fundamental steps in the central dogma of molecular biology. In recent …
makes it one of the fundamental steps in the central dogma of molecular biology. In recent …