Network alignment and motif discovery in dynamic networks

P Cinaglia, M Cannataro - … Modeling Analysis in Health Informatics and …, 2022 - Springer
In the-omics era, bioinformatics technologies allowed the development of several
approaches useful to analyze biological systems. To provide a deep insight into a biological …

Spectral clustering on protein-protein interaction networks via constructing affinity matrix using attributed graph embedding

K Berahmand, E Nasiri, Y Li - Computers in Biology and Medicine, 2021 - Elsevier
The identification of protein complexes in protein-protein interaction networks is the most
fundamental and essential problem for revealing the underlying mechanism of biological …

Community detection in protein-protein interaction networks and applications

I Manipur, M Giordano, M Piccirillo… - IEEE/ACM …, 2021 - ieeexplore.ieee.org
The ability to identify and characterize not only the protein-protein interactions but also their
internal modular organization through network analysis is fundamental for understanding …

Gapseq: informed prediction of bacterial metabolic pathways and reconstruction of accurate metabolic models

J Zimmermann, C Kaleta, S Waschina - Genome biology, 2021 - Springer
Genome-scale metabolic models of microorganisms are powerful frameworks to predict
phenotypes from an organism's genotype. While manual reconstructions are laborious …

Decision tree classifier based on topological characteristics of subgraph for the mining of protein complexes from large scale PPI networks

TR Sahoo, S Patra, S Vipsita - Computational Biology and Chemistry, 2023 - Elsevier
The growing accessibility of large-scale protein interaction data demands extensive
research to understand cell organization and its functioning at the network level …

PC2P: parameter-free network-based prediction of protein complexes

S Omranian, A Angeleska, Z Nikoloski - Bioinformatics, 2021 - academic.oup.com
Motivation Prediction of protein complexes from protein–protein interaction (PPI) networks is
an important problem in systems biology, as they control different cellular functions. The …

Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context

V Robin, A Bodein, MP Scott-Boyer… - Frontiers in Molecular …, 2022 - frontiersin.org
At the heart of the cellular machinery through the regulation of cellular functions, protein–
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …

Enhancing coevolutionary signals in protein–protein interaction prediction through clade-wise alignment integration

T Fang, D Szklarczyk, R Hachilif, C von Mering - Scientific Reports, 2024 - nature.com
Protein–protein interactions (PPIs) play essential roles in most biological processes. The
binding interfaces between interacting proteins impose evolutionary constraints that have …

Protein complexes form a basis for complex hybrid incompatibility

KBS Swamy, SC Schuyler, JY Leu - Frontiers in genetics, 2021 - frontiersin.org
Proteins are the workhorses of the cell and execute many of their functions by interacting
with other proteins forming protein complexes. Multi-protein complexes are an admixture of …

Molecular computing and bioinformatics

X Liang, W Zhu, Z Lv, Q Zou - Molecules, 2019 - mdpi.com
Molecular computing and bioinformatics are two important interdisciplinary sciences that
study molecules and computers. Molecular computing is a branch of computing that uses …