Conditioned flavor avoidance and conditioned gaping: rat models of conditioned nausea

LA Parker - European Journal of Pharmacology, 2014 - Elsevier
Although rats are incapable of vomiting, they demonstrate profound avoidance of a flavor
previously paired with an emetic drug. They also display conditioned gaping reactions …

Effects of prolonged selective serotonin reuptake inhibition on the development and expression of L-DOPA-induced dyskinesia in hemi-parkinsonian rats

MM Conti, CY Ostock, D Lindenbach, AA Goldenberg… - …, 2014 - Elsevier
Dopamine (DA) replacement therapy with l-DOPA is the standard treatment for Parkinson's
disease (PD). Unfortunately chronic treatment often leads to the development of abnormal …

Inverse agonism of cannabinoid CB1 receptors potentiates LiCl‐induced nausea in the conditioned gaping model in rats

CL Limebeer, VK Vemuri, H Bedard… - British journal of …, 2010 - Wiley Online Library
BACKGROUND AND PURPOSE Cannabinoid CB1 receptor antagonists/inverse agonists,
potentiate toxin‐induced nausea and vomiting in animal models. Here, we sought to …

Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ9‐tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism …

EM Rock, MA Sticht, M Duncan, C Stott… - British journal of …, 2013 - Wiley Online Library
Background and Purpose The cannabinoid 1 (CB1) receptor inverse agonists/antagonists,
rimonabant (SR 141716, SR) and AM251, produce nausea and potentiate toxin‐induced …

Toxin-induced aversive context conditioning: Assessing active aversive behaviors conditioned to the context of an automated activity monitor

M Doobay, SK Cross-Mellor, DTO Wah, M Kavaliers… - Physiology & …, 2021 - Elsevier
Lithium chloride (LiCl) is an emetic drug that has been used to create animal models of
anticipatory nausea and conditioned place aversion. In this study we examined escape …

Conditioned disgust in rats (anticipatory nausea) to a context paired with the effects of the toxin LiCl: Influence of sex and the estrous cycle

CJ Cloutier, DL Zevy, M Kavaliers… - Pharmacology …, 2018 - Elsevier
The role of sex and estrous phase in the conditioning of toxin-induced disgust reactions
(anticipatory nausea) to a novel context were examined in adult rats. Conditioned oral …

Electroacupuncture improves antidepressant effects in cums rats by protecting hippocampal synapse and mitochondrion: an ultrastructural and iTRAQ Proteomic …

J Zhang, Z Zhang, J Zhang, Z Zhong… - Evidence‐Based …, 2019 - Wiley Online Library
Electroacupuncture (EA) is considered a complementary therapy for depression. Trials also
found that EA has additive benefits when combined with medication compared with …

Antidepressant-like and anti-oxidative efficacy of Campsis grandiflora flower

HC Yu, J Wu, HX Zhang, HS Zhang… - Journal of Pharmacy …, 2015 - academic.oup.com
Objectives Our study aimed to investigate the antidepressant-like effect of ethyl acetate
extract of the flowers of Campsis grandiflora (EFCG) in a mice model of chronic …

Dopaminergic signaling in prefrontal cortex contributes to the antidepressant effect of electroacupuncture: An iTRAQ‐based proteomics analysis in a rat model of …

J Zhang, J Zhang, Z Zhang, Y Zheng… - The Anatomical …, 2021 - Wiley Online Library
Electroacupuncture (EA) is used as an adjunctive treatment for depression. This study was
conducted to evaluate the efficacy and mechanisms of EA in the depressive rat model …

Acute corticosterone increases conditioned spontaneous orofacial behaviors but fails to influence dose related LiCl-induced conditioned “gaping” responses in a …

KP Ossenkopp, E Biagi, CJ Cloutier, MYT Chan… - European journal of …, 2011 - Elsevier
Acute administration of corticosterone has been shown to facilitate learning in a number of
associative paradigms, including LiCl-induced conditioned taste aversion learning. The …