Thalassemia intermedia encompasses a wide clinical spectrum of beta-thalassemia
phenotypes. Some thalassemia intermedia patients are asymptomatic until adult life …

Beta-thalassemia is due to a defect in the synthesis of the beta-globin chains, leading to
alpha/beta imbalance, ineffective erythropoiesis, and chronic anemia. The spectrum of …

Our understanding of the molecular and pathophysiological mechanisms underlying the
disease process in patients with thalassaemia intermedia (TI) has substantially increased …

Our understanding of the molecular and pathophysiological mechanisms underlying the
disease process in patients with thalassemia intermedia (TI) has substantially increased …

The clinical phenotypes of thalassaemia intermedia (TI) lie between those of thalassaemia
minor and major, although there is substantial clinical overlap between the three conditions …

Thalassemia syndromes are the most common hereditary genetic diseases of mankind.
They result from an imbalance between the number of alpha-and beta-globin chains. When …

Thalassemia intermedia is a genetically diverse group of diseases that is the result of an
imbalance in the production of the alpha and beta chains with ensuing chronic hemolysis …

Thalassemia is an inherited disorder characterized by reduced or absent hemoglobin
synthesis. The pathophysiology stems from the imbalance between the alpha and beta …