Pancreatitis is increasingly recognized as not merely a local inflammation of the pancreas
but also a disease with high frequency of systemic sequelae. Current understanding of the …

Although translational research into autosomal dominant polycystic kidney disease
(ADPKD) and its pathogenesis has made considerable progress, there is presently lack of …

Autosomal dominant polycystic kidney disease (ADPKD) can be caused by mutations in the
PKD1 or PKD2 genes. The PKD1 gene product is a Wnt cell-surface receptor. We previously …

Polycystic kidney disease is characterized by the progressive development of kidney cysts
and declining renal function with frequent development of cysts in other organs including the …

Primary cilia are microtubule-based organelles that mediate various biological processes.
Pancreatic cells are typically ciliated; however, the role of primary cilia in acute pancreatitis …

Objective To describe first episodes of bacterial cholangitis complicating autosomal
dominant polycystic kidney disease (ADPKD) and autosomal dominant polycystic liver …

Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common
inherited kidney disease in the clinic. The predominant clinical manifestation is bilateral and …

Introduction In children, chronic pancreatitis (CP) is usually associated with anatomical
anomalies of the pancreas and biliary tract or is genetically determined. Autosomal …

Background The objective of this study was to determine the incidence of major
hepatointestinal complications in patients with polycystic kidney disease (PKD). Methods We …

Estudos experimentais e clínicos amparam a participação do estresse oxidativo na
progressão da doença renal na doença renal policística autossômica dominante (DRPAD) …