Drosophila neuroblasts, the stem cells of the developing fly brain, have emerged as a key
model system for neural stem cell biology and have provided key insights into the …

The neural circuits governing vital behaviors, such as respiration and locomotion, are
comprised of discrete neuronal populations residing within the brainstem and spinal cord …

Stem cells reside in specialized microenvironments known as niches. During Drosophila
development, glial cells provide a niche that sustains the proliferation of neural stem cells …

Notch is an evolutionarily conserved local cell signaling mechanism that participates in a
variety of cellular processes: cell fate specification, differentiation, proliferation, apoptosis …

In The Birth of the Mind, award-winning cognitive scientist Gary Marcus irrevocably alters the
nature vs. nurture debate by linking the findings of the Human Genome project to the …

Background In the mammalian brain, neural stem cells divide asymmetrically and often
amplify the number of progeny they generate via symmetrically dividing intermediate …

Embryonic cell fates are defined by transcription factors that are rapidly deployed, yet
attempts to visualize these factors in vivo often fail because of slow fluorescent protein …

Brain development in Drosophila is characterized by two neurogenic periods, one during
embryogenesis and a second during larval life. Although much is known about embryonic …

An important question in neuroscience is how stem cells generate neuronal diversity. During
Drosophila embryonic development, neural stem cells (neuroblasts) sequentially express …

Complex behaviors, such as aggression, are comprised of distinct stereospecific behavioral
patterns (modules). How such patterns get wired into nervous systems remains unknown …