Dengue virus: epidemiology, biology, and disease aetiology

SK Roy, S Bhattacharjee - Canadian journal of microbiology, 2021 - cdnsciencepub.com
Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV).
Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each …

Label-free microfluidic cell sorting and detection for rapid blood analysis

N Lu, HM Tay, C Petchakup, L He, L Gong, KK Maw… - Lab on a Chip, 2023 - pubs.rsc.org
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …

Platelet gene expression and function in patients with COVID-19

BK Manne, F Denorme, EA Middleton… - Blood, The Journal …, 2020 - ashpublications.org
There is an urgent need to understand the pathogenesis of coronavirus disease 2019
(COVID-19). In particular, thrombotic complications in patients with COVID-19 are common …

[HTML][HTML] Dengue hemorrhagic fever–A systemic literature review of current perspectives on pathogenesis, prevention and control

WH Wang, AN Urbina, MR Chang… - Journal of Microbiology …, 2020 - Elsevier
Background Dengue is an arboviral disease caused by dengue virus. Symptomatic dengue
infection causes a wide range of clinical manifestations, from mild dengue fever (DF) to …

The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases

L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …

Innate immune receptors in platelets and platelet-leukocyte interactions

PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

COVID-19 induces a hyperactive phenotype in circulating platelets

SP Comer, S Cullivan, PB Szklanna, L Weiss… - PLoS …, 2021 - journals.plos.org
Coronavirus Disease 2019 (COVID-19), caused by the novel Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2), has affected over 30 million globally to date …

The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies

S Zhang, L Wang, G Cheng - Molecular therapy, 2022 - cell.com
The SARS-CoV-2 virus, the pathogen causing COVID-19, has caused more than 200 million
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …

Thrombocytopenia in virus infections

M Raadsen, J Du Toit, T Langerak… - Journal of clinical …, 2021 - mdpi.com
Thrombocytopenia, which signifies a low platelet count usually below 150× 109/L, is a
common finding following or during many viral infections. In clinical medicine, mild …

Structural basis for antibody inhibition of flavivirus NS1–triggered endothelial dysfunction

SB Biering, DL Akey, MP Wong, WC Brown, NTN Lo… - Science, 2021 - science.org
Medically important flaviviruses cause diverse disease pathologies and collectively are
responsible for a major global disease burden. A contributing factor to pathogenesis is …