[HTML][HTML] From NASH to diabetes and from diabetes to NASH: mechanisms and treatment options

A Gastaldelli, K Cusi - JHEP reports, 2019 - Elsevier
The worldwide prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to have
reached 25% or more in adults. NAFLD is prevalent in obese individuals, but may also affect …

[HTML][HTML] Non-alcoholic fatty liver disease and diabetes

JM Hazlehurst, C Woods, T Marjot, JF Cobbold… - Metabolism, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2DM) are common
conditions that regularly co-exist and can act synergistically to drive adverse outcomes. The …

[PDF][PDF] Сахарный диабет 2 типа

АС Аметов - Проблемы и решения, 2014 - e-library.sammu.uz
Аннотация Современная диабетология обращает самое серьезное внимание на
метаболизм жировой ткани потому, что жировая ткань очень тесно связана с …

[HTML][HTML] Sitagliptin in patients with non-alcoholic steatohepatitis: a randomized, placebo-controlled trial

TR Joy, CA McKenzie, RG Tirona… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To evaluate the effect of sitagliptin vs placebo on histologic and non-histologic
parameters of non-alcoholic steatohepatitis (NASH). METHODS Twelve patients with biopsy …

Effects of newer antidiabetic drugs on nonalcoholic fatty liver and steatohepatitis: Think out of the box!

G Ranjbar, DP Mikhailidis, A Sahebkar - Metabolism, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in
Western societies and a major cause of hepatic disease worldwide. Its more severe type …

Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) for the management of nonalcoholic fatty liver disease (NAFLD): a systematic review

X Lv, Y Dong, L Hu, F Lu, C Zhou… - … , diabetes & metabolism, 2020 - Wiley Online Library
There are no licensed drugs for nonalcoholic fatty liver disease (NAFLD), and there is a lack
of consensus on the best outcome measures for controlled trials. This systematic review …

Novel antidiabetic medications for non‐alcoholic fatty liver disease with type 2 diabetes mellitus

Y Sumida, Y Seko, M Yoneda… - Hepatology …, 2017 - Wiley Online Library
Liver‐related diseases are the leading causes of death in patients with type 2 diabetes
mellitus (T2DM) in Japan. Type 2 diabetes mellitus is closely associated with non‐alcoholic …

[HTML][HTML] Effects of sitagliptin on intrahepatic lipid content in patients with non-alcoholic fatty liver disease

X Wang, B Zhao, H Sun, H You, S Qu - Frontiers in endocrinology, 2022 - frontiersin.org
Purpose Dipeptidyl peptidase-4 inhibitors (DPP-4I), key regulators of the actions of incretin
hormones, exert anti-hyperglycemic effects in type 2 diabetes mellitus (T2DM) patients. A …

Comparison of dapagliflozin and teneligliptin in nonalcoholic fatty liver disease patients without type 2 diabetes mellitus: A prospective randomized study

H Tobita, T Yazaki, M Kataoka, S Kotani… - Journal of Clinical …, 2021 - jstage.jst.go.jp
抄録 There are no reports regarding the efficacy of sodium-glucose cotransporter 2 inhibitor
(SGLT2i) and dipeptidyl peptidase 4 inhibitor (DPP4i) administrations in nonalcoholic fatty …

Pharmacokinetic and toxicological considerations for the treatment of diabetes in patients with liver disease

AJ Scheen - Expert opinion on drug metabolism & toxicology, 2014 - Taylor & Francis
Introduction: Patients with type 2 diabetes have an increased risk of chronic liver disease
(CLD) such as non-alcoholic fatty liver disease and steatohepatitis and about one-third of …