Nanostructured cochleates: A multi-layered platform for cellular transportation of therapeutics

P Shende, R Khair, RS Gaud - Drug development and industrial …, 2019 - Taylor & Francis
Among lipid-based nanocarriers, multi-layered cochleates emerge as a novel delivery
system because of prevention of oxidation of hydrophobic and hydrophilic drugs …

Hemin accumulation and identification of a heme‐binding protein clan in K562 cells by proteomic and computational analysis

VDC Tsolaki, SK Georgiou‐Siafis… - Journal of cellular …, 2022 - Wiley Online Library
Heme (iron protoporphyrin IX) is an essential regulator conserved in all known organisms.
We investigated the kinetics of intracellular accumulation of hemin (oxidized form) in human …

The problems associated with enzyme purification

E Dako, AM Bernier, AT Dadie, CK Jankowski - Chemical biology, 2012 - books.google.com
This chapter aims to highlight the difficulties encountered during the purification of native
cellular and membrane-bound enzymes from whole cell extracts. There are many reasons …

On the biocatalytic synthesis of silicone polymers

Y Lu, LS Wong - Faraday Discussions, 2024 - pubs.rsc.org
Polysiloxanes, with poly (dimethyl) siloxane (PDMS) being the most common example, are
widely used in various industrial and consumer applications due to the physicochemical …

Effect of a Counterion on the Glass Transition Temperature (Tg′) during Lyophilization of Ganciclovir Salt Forms

L Kumar, A Baheti, AK Bansal - Molecular Pharmaceutics, 2011 - ACS Publications
This manuscript deals with the effect of a counterion on the glass transition temperature for
lyophilization of ganciclovir salts. Salt forms of ganciclovir, namely, sodium, potassium …

Identification of drought-responsive proteins of sensitive and tolerant tea (Camellia sinensis L) clones under Normal and drought stress conditions

M Rahimi, M Kordrostami, M Mortezavi… - Current …, 2020 - ingentaconnect.com
Background: Tea is one of the most popular calming drinks. Drought is a major
environmental factor that limited the growth and development of plants. Objective: Therefore …

Purifying antibodies raised against Xenopus peptides

MZ Piccinni, MJ Guille - Cold Spring Harbor Protocols, 2020 - cshprotocols.cshlp.org
Antibody production for work in Xenopus involves the immunization of a host with an
antigen, usually a Xenopus protein or peptide alien to the host. The antibody-containing …

Process optimization of albumin-stabilized mitotane nanoparticle preparation by dual centrifugation and first lyophilization study

CJR Zhang - 2022 - munin.uit.no
Albumin-stabilized mitotane nanoparticles intended for intravenous application can serve as
a potential formulation for the treatment of adrenocortical carcinoma. However, the particle …

Cell-type Specific Protein Purification and Identification from Complex Tissues using a Mutant Methionine tRNA Synthetase Mouse Line

B Nassim-Assir, DO Corredera… - JoVE (Journal of …, 2022 - jove.com
Understanding protein homeostasis in vivo is key to knowing how the cells work in both
physiological and disease conditions. The present protocol describes in vivo labeling and …

[PDF][PDF] Designing protic ionic liquids to be compatible with biomolecules

HC Broomhall - 2021 - researchrepository.rmit.edu.au
Identifying and characterising the conditions in which proteins and other biomolecules
remain stable within a solvent is a crucial factor in many different branches of biochemical …