The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

Gating of social reward by oxytocin in the ventral tegmental area

LW Hung, S Neuner, JS Polepalli, KT Beier, M Wright… - Science, 2017 - science.org
The reward generated by social interactions is critical for promoting prosocial behaviors.
Here we present evidence that oxytocin (OXT) release in the ventral tegmental area (VTA), a …

[HTML][HTML] Oxytocin enhances social recognition by modulating cortical control of early olfactory processing

LL Oettl, N Ravi, M Schneider, MF Scheller… - Neuron, 2016 - cell.com
Oxytocin promotes social interactions and recognition of conspecifics that rely on olfaction in
most species. The circuit mechanisms through which oxytocin modifies olfactory processing …

Hippocampal oxytocin receptors are necessary for discrimination of social stimuli

T Raam, KM McAvoy, A Besnard, AH Veenema… - Nature …, 2017 - nature.com
Oxytocin receptor (Oxtr) signaling in neural circuits mediating discrimination of social stimuli
and affiliation or avoidance behavior is thought to guide social recognition. Remarkably, the …

Biased oxytocinergic modulation of midbrain dopamine systems

L Xiao, MF Priest, J Nasenbeny, T Lu, Y Kozorovitskiy - Neuron, 2017 - cell.com
The release of dopamine (DA) regulates rewarding behavior and motor actions through
striatum-targeting efferents from ventral tegmental area (VTA) and substantia nigra pars …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

Oxytocin signaling in the central amygdala modulates emotion discrimination in mice

V Ferretti, F Maltese, G Contarini, M Nigro, A Bonavia… - Current Biology, 2019 - cell.com
Recognition of other's emotions influences the way social animals interact and adapt to the
environment. The neuropeptide oxytocin (OXT) has been implicated in different aspects of …

Insular cortex mediates approach and avoidance responses to social affective stimuli

MM Rogers-Carter, JA Varela, KB Gribbons… - Nature …, 2018 - nature.com
Social animals detect the affective states of conspecifics and utilize this information to
orchestrate social interactions. In a social affective preference text in which experimental …

Neuroanatomical substrates of rodent social behavior: the medial prefrontal cortex and its projection patterns

J Ko - Frontiers in neural circuits, 2017 - frontiersin.org
Social behavior encompasses a number of distinctive and complex constructs that form the
core elements of human imitative culture, mainly represented as either affiliative or …