Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

The fungal infections are relatively common in humans that can range from common, mild
superficial infections to life-threatening invasive infections. Most of the pathogenic fungi are …

Highlights•Our limited arsenal of antifungals is threatened by drug-resistant fungal
pathogens.•Inherent resistance is when all strains of a species show antifungal …

Candida parapsilosis is the second most common Candida species isolated in Asia,
Southern Europe, and Latin America and is often involved in invasive infections that …

The fungal pathogens Candida albicans, Cryptococcus neoformans, and Aspergillus
fumigatus have transitioned from a rare curiosity to a leading cause of human mortality. The …

The polymorphic fungus Candida albicans is a member of the normal human microbiome. In
most individuals, C. albicans resides as a lifelong, harmless commensal. Under certain …

Antifungal therapy is a central component of patient management for acute and chronic
mycoses. Yet, treatment choices are restricted because of the sparse number of antifungal …

Invasive, life-threatening fungal infections are an important cause of morbidity and mortality,
particularly for patients with compromised immune function. The number of therapeutic …

The cell wall is an essential component in fungal homeostasis. The lack of a covering wall in
human cells makes this component an attractive target for antifungal development. The host …

Invasive fungal infections are an important infection concern for patients with underlying
immunosuppression. Antifungal therapy is a critical component of patient care, but …