Region-specific characteristics of astrocytes and microglia: a possible involvement in aging and diseases
J Lee, SW Kim, KT Kim - Cells, 2022 - mdpi.com
Although different regions of the brain are dedicated to specific functions, the intra-and inter-
regional heterogeneity of astrocytes and microglia in these regions has not yet been fully …
regional heterogeneity of astrocytes and microglia in these regions has not yet been fully …
Acute cerebellar inflammation and related ataxia: mechanisms and pathophysiology
MSA Parvez, G Ohtsuki - Brain sciences, 2022 - mdpi.com
The cerebellum governs motor coordination and motor learning. Infection with external
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …
Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain
Cerebellar outputs take polysynaptic routes to reach the rest of the brain, impeding
conventional tracing. Here, we quantify pathways between the cerebellum and forebrain by …
conventional tracing. Here, we quantify pathways between the cerebellum and forebrain by …
[HTML][HTML] Cerebellar transcranial direct current stimulation in spinocerebellar ataxia type 3: a randomized, double-blind, sham-controlled trial
RP Maas, S Teerenstra, I Toni, T Klockgether… - …, 2022 - Elsevier
Repeated sessions of cerebellar anodal transcranial direct current stimulation (tDCS) have
been suggested to modulate cerebellar-motor cortex (M1) connectivity and decrease ataxia …
been suggested to modulate cerebellar-motor cortex (M1) connectivity and decrease ataxia …
Consensus paper: novel directions and next steps of non-invasive brain stimulation of the cerebellum in health and disease
The cerebellum is involved in multiple closed-loops circuitry which connect the cerebellar
modules with the motor cortex, prefrontal, temporal, and parietal cortical areas, and …
modules with the motor cortex, prefrontal, temporal, and parietal cortical areas, and …
Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia
LN Miterko, T Lin, J Zhou, ME van der Heijden… - Nature …, 2021 - nature.com
Deep brain stimulation (DBS) relieves motor dysfunction in Parkinson's disease, and other
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
Novel cerebello-amygdala connections provide missing link between cerebellum and limbic system
SJ Jung, K Vlasov, AF D'Ambra, A Parigi… - Frontiers in systems …, 2022 - frontiersin.org
The cerebellum is emerging as a powerful regulator of cognitive and affective processing
and memory in both humans and animals and has been implicated in affective disorders …
and memory in both humans and animals and has been implicated in affective disorders …
Activation of TrkB-Akt signaling rescues deficits in a mouse model of SCA6
Spinocerebellar ataxia type 6 (SCA6) is a neurodegenerative disease resulting in motor
coordination deficits and cerebellar pathology. Expression of brain-derived neurotrophic …
coordination deficits and cerebellar pathology. Expression of brain-derived neurotrophic …
Mitochondrial damage and impaired mitophagy contribute to disease progression in SCA6
Abstract Spinocerebellar ataxia type 6 (SCA6) is a neurodegenerative disease that
manifests in midlife and progressively worsens with age. SCA6 is rare, and many patients …
manifests in midlife and progressively worsens with age. SCA6 is rare, and many patients …
[HTML][HTML] A mitochondrial-targeted antioxidant (MitoQ) improves motor coordination and reduces Purkinje cell death in a mouse model of ARSACS
Mitochondrial deficits have been observed in animal models of Autosomal-recessive spastic
ataxia of Charlevoix-Saguenay (ARSACS) and in patient-derived fibroblasts. We …
ataxia of Charlevoix-Saguenay (ARSACS) and in patient-derived fibroblasts. We …