The power of computational proteomics platforms to decipher protein-protein interactions

M González-Avendaño, J López… - Current Opinion in …, 2024 - Elsevier
Adopting computational tools for analyzing extensive biological datasets has profoundly
transformed our understanding and interpretation of biological phenomena. Innovative …

Multi-level bioinformatics resources support drug target discovery of protein–protein interactions

JX Liu, X Zhang, YQ Huang, GF Hao, GF Yang - Drug Discovery Today, 2024 - Elsevier
Drug discovery often begins with a new target. Protein–protein interactions (PPIs) are crucial
to multitudinous cellular processes and offer a promising avenue for drug-target discovery …

Exploration of functional relations among differentially co-expressed genes identifies regulators in glioblastoma

S Kumar, DT Sarmah, A Paul, S Chatterjee - Computational Biology and …, 2024 - Elsevier
The conventional computational approaches to investigating a disease confront inherent
constraints as they often need to improve in delving beyond protein functional associations …

An antisense oligonucleotide-based strategy to ameliorate cognitive dysfunction in the 22q11. 2 Deletion Syndrome

P Thakur, M Lackinger, A Diamantopoulou, S Rao… - bioRxiv, 2022 - biorxiv.org
Adults and children with the 22q11. 2 Deletion Syndrome demonstrate cognitive, social and
emotional impairments and high risk for schizophrenia. Work in mouse model of the 22q11 …