Differential cell-cycle control by oscillatory versus sustained Hes1 expression via p21
Y Maeda, A Isomura, T Masaki, R Kageyama - Cell reports, 2023 - cell.com
Oscillatory Hes1 expression activates cell proliferation, while high and sustained Hes1
expression induces quiescence, but the mechanism by which Hes1 differentially controls …
expression induces quiescence, but the mechanism by which Hes1 differentially controls …
[HTML][HTML] Prosaposin maintains adult neural stem cells in a state associated with deep quiescence
M Labusch, M Thetiot, E Than-Trong, D Morizet… - Stem Cell Reports, 2024 - cell.com
In most vertebrates, adult neural stem cells (NSCs) continuously give rise to neurons in
discrete brain regions. A critical process for maintaining NSC pools over long periods of time …
discrete brain regions. A critical process for maintaining NSC pools over long periods of time …
The cellular Notch1 Protein Promotes KSHV reactivation in an Rta-dependent manner
J DeCotiis-Mauro, SM Han, H Mello… - Journal of …, 2024 - journals.asm.org
The cellular Notch signal transduction pathway is intimately associated with infections by
Kaposi's sarcoma-associated herpesvirus (KSHV) and other gamma-herpesviruses. RBP-Jk …
Kaposi's sarcoma-associated herpesvirus (KSHV) and other gamma-herpesviruses. RBP-Jk …
Key age-imposed signaling changes that are responsible for the decline of stem cell function
This chapter analyzes recent developments in the field of signal transduction of ageing with
the focus on the age-imposed changes in TGF-beta/pSmad, Notch, Wnt/beta-catenin, and …
the focus on the age-imposed changes in TGF-beta/pSmad, Notch, Wnt/beta-catenin, and …
Investigating the mechanisms of perinatal neuron degeneration, survival, and their differentiation from neural precursor cells of the V-SVZ
A Kolaj - 2023 - search.proquest.com
For the formation and maintenance of functional neuronal networks, the generation of
neurons from their progenitors developmentally as well as their continued survival once the …
neurons from their progenitors developmentally as well as their continued survival once the …
Aging Microglia and Their Impact on Neural Stem Cell Function in the Subventricular Zone
SJ Harrison - 2024 - search.proquest.com
Neurogenesis, or the production of new neurons, occurs throughout life in neural stem cell
(NSC) niches of the brain. There are two neurogenic niches in the brain, the subventricular …
(NSC) niches of the brain. There are two neurogenic niches in the brain, the subventricular …
[PDF][PDF] マウス神経幹細胞Radial glial cell の維持と姉妹細胞の非対称性を生むNotch の活性化機構
間瀬俊 - 2021 - repository.kulib.kyoto-u.ac.jp
要旨マウスの大脳背側の神経発生では, 神経幹細胞が対称分裂で増殖し, その後非対称分裂
によって神経細胞を生み出す. 未分化性を維持しながら非対称分裂を継続するためには …
によって神経細胞を生み出す. 未分化性を維持しながら非対称分裂を継続するためには …