Modulatory role of α-MSH in hippocampal-dependent memory impairment, synaptic plasticity changes, oxidative stress, and astrocyte reactivity induced by short-term …
G Herrera, MC Becerra, M Lasaga, T Scimonelli - Neuropharmacology, 2023 - Elsevier
High-fat diet (HFD) consumption is associated with cognitive deficits and neurodegenerative
diseases. Since the hippocampus is extremely sensitive to pathophysiological changes …
diseases. Since the hippocampus is extremely sensitive to pathophysiological changes …
Acetobacter pasteurianus BP2201 alleviates alcohol‐induced hepatic and neuro‐toxicity and modulate gut microbiota in mice
X Wen, Z Wang, Q Liu, DJ Lessing… - Microbial …, 2023 - Wiley Online Library
The excessive consumption of alcohol results in a dysbiosis of the gut microbiota, which
subsequently impairs the gut microbiota‐brain/liver axes and induces cognitive dysfunction …
subsequently impairs the gut microbiota‐brain/liver axes and induces cognitive dysfunction …
Irisin attenuates ethanol-induced behavioral deficits in mice through activation of Nrf2 and inhibition of NF-κB pathways
X Jiang, Q Yan, W Lao, Q Lin, H Cao, L Chen… - Metabolic Brain …, 2023 - Springer
This study aims to investigate the effect of irisin on ethanol-induced behavioral deficits and
explore the underlying mechanisms. A mouse model of ethanol addiction/withdrawal was …
explore the underlying mechanisms. A mouse model of ethanol addiction/withdrawal was …
Mitochondria-tau association promotes cognitive decline and hippocampal bioenergetic deficits during the aging
MA Olesen, E Pradenas, F Villavicencio-Tejo… - Free Radical Biology …, 2024 - Elsevier
Current studies indicate that pathological modifications of tau are associated with
mitochondrial dysfunction, synaptic failure, and cognitive decline in neurological disorders …
mitochondrial dysfunction, synaptic failure, and cognitive decline in neurological disorders …
Hemichannels contribute to mitochondrial Ca2+ and morphology alterations evoked by ethanol in astrocytes
TF Alvear, A Farias-Pasten, SA Vergara… - Frontiers in Cell and …, 2024 - frontiersin.org
Alcohol, a toxic and psychoactive substance with addictive properties, severely impacts life
quality, leading to significant health, societal, and economic consequences. Its rapid …
quality, leading to significant health, societal, and economic consequences. Its rapid …
Activation of the Nrf2 pathway prevents mitochondrial dysfunction induced by caspase-3 cleaved tau: implications for Alzheimer's disease
F Villavicencio-Tejo, MA Olesen, A Aránguiz… - Antioxidants, 2022 - mdpi.com
Alzheimer's disease (AD) is characterized by memory and cognitive impairment,
accompanied by the accumulation of extracellular deposits of amyloid β-peptide (Aβ) and …
accompanied by the accumulation of extracellular deposits of amyloid β-peptide (Aβ) and …
Protective Effect of Sargassum fusiforme Fucoidan against Ethanol-Induced Oxidative Damage in In Vitro and In Vivo Models
Our previous studies have evaluated the bioactivities of a fucoidan isolated from Sargassum
fusiforme (SF-F). To further investigate the health benefit of SF-F, in the present study, the …
fusiforme (SF-F). To further investigate the health benefit of SF-F, in the present study, the …
The Mechanism of TNF‐α‐Mediated Accumulation of Phosphorylated Tau Protein and Its Modulation by Propofol in Primary Mouse Hippocampal Neurons: Role of …
L Zhang, H Song, J Ding, D Wang, S Zhu… - Oxidative Medicine …, 2022 - Wiley Online Library
Background. Neuroinflammation‐induced phosphorylated Tau (p‐Tau) deposition in central
nervous system contributes to neurodegenerative disorders. Propofol possesses …
nervous system contributes to neurodegenerative disorders. Propofol possesses …
Activating MC4R Promotes Functional Recovery by Repressing Oxidative Stress-Mediated AIM2 Activation Post-spinal Cord Injury
Y Wang, N Fang, Y Wang, Y Geng, Y Li - Molecular Neurobiology, 2024 - Springer
Spinal cord injury (SCI) is a destructive neurological trauma that induces permanent sensory
and motor impairment as well as a deficit in autonomic physiological function. Melanocortin …
and motor impairment as well as a deficit in autonomic physiological function. Melanocortin …
Quercetin promotes behavioral recovery and biomolecular changes of melanocortin-4 receptor in mice with ischemic stroke
Objectives Ischemic stroke is known as a common causes of disability, lower psychological
well-being as well as preventable death. The pathogenesis of ischemic stroke process …
well-being as well as preventable death. The pathogenesis of ischemic stroke process …