For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Skeletal muscle is the most abundant tissue in healthy individuals and it has important roles
in health beyond voluntary movement. The overall mass and energy requirements of …

Background Blood-based test for predicting disease progression and early diagnosis of
Parkinson's disease (PD) is an unmet need in the clinic. The profiles of microRNAs …

Context Previous investigations on skeletal muscle health in type 1 diabetes (T1D) have
generally focused on later stages of disease progression where comorbidities are present …

Background Ageing of skeletal muscle is characterized in some by muscle fiber type
grouping due to denervation-reinnervation cycles, but the severity of fiber type grouping …

The skeletal muscle hypertrophic response to resistance exercise training (RT) is highly
variable across individuals. The molecular underpinnings of this heterogeneity are unclear …

Parkinson's disease (PD) is the most common motor neurodegenerative disease, and
neuromuscular function deficits associated with PD contribute to disability. Targeting these …

Cardiac baroreflex and leg muscles activation are two important mechanisms for blood
pressure regulation, failure of which could result in syncope and falls. Parkinson's disease is …

Aim While manual quantification is still considered the gold standard for skeletal muscle
histological analysis, it is time‐consuming and prone to investigator bias. To address this …

There is increasing evidence that neurodegenerative disorders including the Parkinsonian
syndromes are associated with impaired skeletal muscle health, manifesting as wasting and …