Gastrointestinal stromal tumors (GISTs) are the most common malignant subepithelial
lesions (SELs) of the gastrointestinal tract. They originate from the interstitial cells of Cajal …

Gastrointestinal stromal tumours (GISTs) are mesenchymal neoplasms that arise in the
gastrointestinal tract, usually in the stomach or the small intestine and rarely elsewhere in …

Deregulated protein tyrosine kinase activity is central to the pathogenesis of human cancers.
Targeted therapy in the form of selective tyrosine kinase inhibitors (TKIs) has transformed …

Background Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal
tumors of the gastrointestinal tract. Neoplastic GIST cells seem to arise from a common …

Biomarkers currently play an important role in the detection and management of patients
with several different types of gastrointestinal cancer, especially colorectal, gastric, gastro …

Background Imatinib is approved worldwide for use in gastrointestinal stromal tumours
(GIST). We aimed to assess dose dependency of response and progression-free survival …

The NCCN Soft Tissue Sarcoma Guidelines include a subsection about treatment
recommendations for gastrointestinal stromal tumors (GISTs). The standard of practice …

Gastrointestinal stromal tumours are the most common mesenchymal neoplasm of the
gastrointestinal tract and are highly resistant to conventional chemotherapy and …

Purpose The Gastrointestinal Stromal Tumor Meta-Analysis Group (MetaGIST) project aims
to additionally explore the data of the two large, randomized, cooperative-group studies …

Background The management of gastrointestinal stromal tumors (GIST) has evolved very
rapidly in the last 4 years. The objectives of this international consensus meeting were to …