Mechanisms of Schwann cell plasticity involved in peripheral nerve repair after injury

G Nocera, C Jacob - Cellular and Molecular Life Sciences, 2020 - Springer
The great plasticity of Schwann cells (SCs), the myelinating glia of the peripheral nervous
system (PNS), is a critical feature in the context of peripheral nerve regeneration following …

The success and failure of the Schwann cell response to nerve injury

KR Jessen, R Mirsky - Frontiers in cellular neuroscience, 2019 - frontiersin.org
The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin)
and myelin phenotypes, which are specialized to meet the needs of small and large …

[HTML][HTML] Biopolymer-based composites for tissue engineering applications: A basis for future opportunities

P Zarrintaj, F Seidi, MY Azarfam, MK Yazdi… - Composites Part B …, 2023 - Elsevier
Biomimetic scaffolds supporting tissue regeneration are complex materials with
multifunctional characteristics. The unique biocompatibility and biodegradability of …

[HTML][HTML] Schwann cell functions in peripheral nerve development and repair

M Bosch-Queralt, R Fledrich, RM Stassart - Neurobiology of disease, 2023 - Elsevier
The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

Migrating Schwann cells direct axon regeneration within the peripheral nerve bridge

Q Min, DB Parkinson, XP Dun - Glia, 2021 - Wiley Online Library
Schwann cells within the peripheral nervous system possess a remarkable regenerative
potential. Current research shows that peripheral nerve‐associated Schwann cells possess …

Repair Schwann cell update: Adaptive reprogramming, EMT, and stemness in regenerating nerves

KR Jessen, P Arthur‐Farraj - Glia, 2019 - Wiley Online Library
Schwann cells respond to nerve injury by cellular reprogramming that generates cells
specialized for promoting regeneration and repair. These repair cells clear redundant …

Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases

L Mei, KA Nave - Neuron, 2014 - cell.com
Neuregulins (NRGs) comprise a large family of growth factors that stimulate ERBB receptor
tyrosine kinases. NRGs and their receptors, ERBBs, have been identified as susceptibility …

Implantable Zinc–Oxygen Battery for In Situ Electrical Stimulation‐Promoted Neural Regeneration

L Li, D Li, Y Wang, T Ye, E He, Y Jiao… - Advanced …, 2023 - Wiley Online Library
Electrical stimulation is a promising strategy for treating neural diseases. However, current
energy suppliers cannot provide effective power for in situ electrical stimulation. Here, an …

Nerve physiology: mechanisms of injury and recovery

RMG Menorca, TS Fussell, JC Elfar - Hand clinics, 2013 - hand.theclinics.com
Peripheral nerve injuries are common conditions with broad-ranging groups of symptoms,
depending on the severity and nerves involved. Although much knowledge exists on the …

Schwann cell myelination

JL Salzer - Cold Spring Harbor perspectives in biology, 2015 - cshperspectives.cshlp.org
Myelinated nerve fibers are essential for the rapid propagation of action potentials by
saltatory conduction. They form as the result of reciprocal interactions between axons and …