Isoniazid-resistant tuberculosis: a cause for concern?
The drug isoniazid (INH) is a key component of global tuberculosis (TB) control
programmes. It is estimated, however, that 16.1% of TB disease cases in the former Soviet …
programmes. It is estimated, however, that 16.1% of TB disease cases in the former Soviet …
Targeted next-generation sequencing to diagnose drug-resistant tuberculosis: a systematic review and meta-analysis
TC Schwab, L Perrig, PC Göller… - The Lancet Infectious …, 2024 - thelancet.com
Background Targeted next-generation sequencing (NGS) can rapidly and simultaneously
detect mutations associated with resistance to tuberculosis drugs across multiple gene …
detect mutations associated with resistance to tuberculosis drugs across multiple gene …
Detection of isoniazid, fluoroquinolone, ethionamide, amikacin, kanamycin, and capreomycin resistance by the Xpert MTB/XDR assay: a cross-sectional multicentre …
A Penn-Nicholson, SB Georghiou… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background The WHO End TB Strategy requires drug susceptibility testing and
treatment of all people with tuberculosis, but second-line diagnostic testing with line-probe …
treatment of all people with tuberculosis, but second-line diagnostic testing with line-probe …
Drug-resistant tuberculosis: is India ready for the challenge?
S Chatterjee, H Poonawala, Y Jain - BMJ global health, 2018 - gh.bmj.com
WHaT Is THe burden of dr-Tb In IndIa? Globally, 4.1% of new TB cases are reported to be
MDR. 1 Concordant with previous surveys, the First National Anti-Tuberculosis Drug …
MDR. 1 Concordant with previous surveys, the First National Anti-Tuberculosis Drug …
[HTML][HTML] Latent tuberculosis: interaction of virulence factors in Mycobacterium tuberculosis
S Sundararajan, R Muniyan - Molecular Biology Reports, 2021 - Springer
Tuberculosis (TB) remains a prominent health concern worldwide. Besides extensive
research and vaccinations available, attempts to control the pandemic are cumbersome due …
research and vaccinations available, attempts to control the pandemic are cumbersome due …
Systematic review of mutations associated with isoniazid resistance points to continuing evolution and subsequent evasion of molecular detection, and potential for …
SJ Valafar - Antimicrobial Agents and Chemotherapy, 2021 - Am Soc Microbiol
Molecular testing is rapidly becoming an integral component of global tuberculosis (TB)
control. Uncommon mechanisms of resistance escape detection by these platforms and …
control. Uncommon mechanisms of resistance escape detection by these platforms and …
Molecular characterisation of second-line drug resistance among drug resistant tuberculosis patients tested in Uganda: a two and a half-year's review
D Mujuni, DL Kasemire, I Ibanda, J Kabugo… - BMC Infectious …, 2022 - Springer
Background Second-line drug resistance (SLD) among tuberculosis (TB) patients is a
serious emerging challenge towards global control of the disease. We characterized SLD …
serious emerging challenge towards global control of the disease. We characterized SLD …
Epidemiological characteristics and risk factors of multidrug-resistant tuberculosis in Luoyang, China
Z Wang, Y Hou, T Guo, T Jiang, L Xu, H Hu… - Frontiers in Public …, 2023 - frontiersin.org
Objective We aimed to examine the prevalence of multidrug-resistant tuberculosis (MDR-TB)
in Luoyang, China, identify related risk factors, inform clinical practices, and establish …
in Luoyang, China, identify related risk factors, inform clinical practices, and establish …
Differential expression of resistant and efflux pump genes in MDR-TB isolates
Background: Numerous investigations demonstrate efflux as a worldwide bacterial mode of
action which contributes to the resistance of drugs. The activity of antibiotics, which subjects …
action which contributes to the resistance of drugs. The activity of antibiotics, which subjects …
Regional distribution of Mycobacterium tuberculosis infection and resistance to rifampicin and isoniazid as determined by high-resolution melt analysis
Z Wang, T Guo, T Jiang, Z Zhao, X Zu, L Li… - BMC Infectious …, 2022 - Springer
Background Identifying the transmission mode and resistance mechanism of Mycobacterium
tuberculosis (MTB) is key to prevent disease transmission. However, there is a lack of …
tuberculosis (MTB) is key to prevent disease transmission. However, there is a lack of …