As an ancient infectious disease, tuberculosis (TB) is still the leading cause of death from a
single infectious agent worldwide. Latent TB infection (LTBI) has been recognized as the …

Glutathione (GSH) is an antioxidant in human cells that is utilized to prevent damage
occurred by reactive oxygen species, free radicals, peroxides, lipid peroxides, and heavy …

Background Diagnosing tuberculosis (TB) in children is challenging due to paucibacillary
disease, and lack of ability for microbiologic confirmation. Hence, we measured the plasma …

Background Discriminating active tuberculosis (ATB) from latent tuberculosis infection (LTBI)
remains challenging. The present study aims to evaluate the performance of diagnostic …

Background The early diagnosis of tuberculosis using novel non-sputum-based biomarkers
is of high priority in the End TB strategy. MicroRNAs (miRNAs) are significant regulators of …

Being among the top 10 causes of adult deaths, tuberculosis (TB) disease is considered a
major global public health concern to address. The human tuberculosis pathogen …

While the exploration into biomolecules for diagnostic and prognostic devices continues to
develop, many molecules continue to be examined for individual diseases or treatments …

Background Previous meta-analysis regarding the performance of QuantiFERON Gold-In-
Tube in children have yielded contrasting results. Emerging data in children younger than 5 …

There is an urgent need for accurate and sensitive diagnostic tools that can overcome the
current challenge to distinguish individuals with latent tuberculosis infection (LTBI) from …

Introduction The risk of progression to tuberculosis disease is highest within the first year
after M. tuberculosis infection (TBI). We hypothesize that people with newly acquired TBI …