Cadmium toxicity: a role in bone cell function and teeth development

Y Ma, D Ran, X Shi, H Zhao, Z Liu - Science of The Total Environment, 2021 - Elsevier
Cadmium (Cd) is a widespread environmental contaminant that causes severe bone
metabolism disease, such as osteoporosis, osteoarthritis, and osteomalacia. The present …

Associations of blood and urinary heavy metals with rheumatoid arthritis risk among adults in NHANES, 1999–2018

L Chen, Q Sun, S Peng, T Tan, G Mei, H Chen, Y Zhao… - Chemosphere, 2022 - Elsevier
Heavy metals exposure has been widely recognized as a risk factor for human health.
However, limited information is available about the impacts of heavy metals on rheumatoid …

Exposure to As-, Cd-, and Pb-mixture induces Aβ, amyloidogenic APP processing and cognitive impairments via oxidative stress-dependent neuroinflammation in …

A Ashok, NK Rai, S Tripathi… - Toxicological …, 2015 - academic.oup.com
Environmental pollutants act as risk factors for Alzheimer's disease (AD), mainly affecting the
aging population. We investigated early manifestations of AD-like pathology by a mixture of …

Environmental factors impacting bone-relevant chemokines

JT Smith, AD Schneider, KM Katchko, C Yun… - Frontiers in …, 2017 - frontiersin.org
Chemokines play an important role in normal bone physiology and the pathophysiology of
many bone diseases. The recent increased focus on the individual roles of this class of …

Elevated lead levels and adverse effects on natural killer cells in children from an electronic waste recycling area

Y Zhang, X Huo, J Cao, T Yang, L Xu, X Xu - Environmental pollution, 2016 - Elsevier
Lead (Pb) has been proved to exert immunotoxicity to influence immune homeostasis in
humans. To monitor the internal Pb level and evaluate its effect on natural killer (NK) cells …

From the cover: arsenic induces hippocampal neuronal apoptosis and cognitive impairments via an up-regulated BMP2/Smad-dependent reduced BDNF/TrkB …

R Pandey, V Rai, J Mishra, K Mandrah… - Toxicological …, 2017 - academic.oup.com
Arsenic promotes hippocampal neuronal damage inducing cognitive impairments. However,
mechanism arbitrating arsenic-mediated cognitive deficits remains less-known. Here, we …

[HTML][HTML] Study on the relationship between age and the concentrations of heavy metal elements in human bone

L Chang, S Shen, Z Zhang, X Song… - Annals of translational …, 2018 - ncbi.nlm.nih.gov
Background Excessive amounts of heavy metals such as cadmium, chromium, cobalt, lead,
thallium, and manganese are extremely harmful to the human body. These elements can …

Arsenic induces differential neurotoxicity in male, female, and E2-deficient females: Comparative effects on hippocampal neurons and cognition in adult rats

R Pandey, A Garg, K Gupta, P Shukla, K Mandrah… - Molecular …, 2022 - Springer
We earlier reported that arsenic induced hippocampal neuronal loss, causing cognitive
dysfunctions in male rats. This neuronal damage mechanism involved an altered bone …

Arsenic Induces GSK3β-Dependent p-Tau, Neuronal Apoptosis, and Cognitive Impairment via an Interdependent Hippocampal ERα and IL-1/IL-1R1 Mechanism in …

K Gupta, J Vishwakarma, A Garg, R Pandey… - Toxicological …, 2022 - academic.oup.com
Arsenic is an environmental contaminant with potential neurotoxicity. We previously reported
that arsenic promoted hippocampal neuronal apoptosis, inducing cognitive loss. Here, we …

Joint action toxicity of arsenic (As) and lead (Pb) mixtures in developing zebrafish

K Kiper, JL Freeman - Biomolecules, 2022 - mdpi.com
Arsenic (As) and lead (Pb) are environmental pollutants found in common sites and linked to
similar adverse health effects. Multiple studies have investigated the toxicity of each metal …