In recent decades, transient and highly reactive ortho-quinodimethanes (o-QDMs), ortho-
quinone methides (o-QMs) and aza-ortho-quinone methides (aza-o-QMs) have attracted …

Abstract Development of new methods of heterocyclic synthesis is still a topical issue. In this
connection, the trend related to the use of highly reactive o-quinone methides for the …

Organometallic quinone methides (OM-QMs) have unique chemical and biological
properties compared to their purely organic counterparts, but their originality has not …

A novel Lewis base-catalyzed [4+ 3] annulation process for the construction of benzo [b]
oxepine scaffolds has been developed. 1, 4-Diazabicyclo [2.2. 2] octane (DABCO) promotes …

Fast, selective and facile functionalization of biologically relevant molecules is a pursuit of
ever‐growing importance. A promising approach in this regard employs the high reactivity of …

Hydride transfer enabled the first success of the regioselective dearomatization of indoles in
the carbocyclic ring and the pyrrole ring, which was induced by ortho-quinone methides and …

The review summarizes and systematizes the [4+ 2]-cycloaddition reactions of o-quinone
methides with electron-rich and electron-deficient olefins. The electron-rich substrates …

Quinone methides (QMs) are considered to be highly reactive intermediates because of their
aromatization both in chemical and biological systems. Being highly accessible, quinone …

Benzylic carbocations bearing an ortho-or para-hydroxyl group can be stabilized by forming
quinone methides, which have been explored in enantioselective synthesis. However, those …

Quinone methides are well-established intermediates in asymmetric synthesis. In contrast,
their extended analogues with the carbonyl and methide units distributed across two …