Macrophage polarization in physiological and pathological pregnancy

Y Yao, XH Xu, L Jin - Frontiers in immunology, 2019 - frontiersin.org
The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

Monocytes and macrophages in pregnancy: The good, the bad, and the ugly

H True, M Blanton, S Sureshchandra… - Immunological …, 2022 - Wiley Online Library
A successful human pregnancy requires precisely timed adaptations by the maternal
immune system to support fetal growth while simultaneously protecting mother and fetus …

Adaptive immune responses during pregnancy

AC Zenclussen - American Journal of Reproductive …, 2013 - Wiley Online Library
It has long been believed that there is no immune interaction between mother and
conceptus during pregnancy. This concept changed after evidence was provided that the …

Pregnancy-specific glycoproteins: complex gene families regulating maternal-fetal interactions.

T Moore, GS Dveksler - International Journal of …, 2014 - search.ebscohost.com
The pregnancy-specific glycoproteins (PSGs) are the most abundant trophoblastic proteins
in maternal blood during human pregnancy and they appear to be exclusive to species with …

Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia

Y Zhou, MJ Gormley, NM Hunkapiller… - The Journal of …, 2013 - Am Soc Clin Investig
During human pregnancy, a subset of placental cytotrophoblasts (CTBs) differentiates into
cells that aggressively invade the uterus and its vasculature, anchoring the progeny and …

Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations

T Moore, JM Williams, MA Becerra-Rodriguez… - …, 2022 - rep.bioscientifica.com
Pregnancy-specific glycoproteins (PSGs) are members of the immunoglobulin superfamily
and are closely related to the predominantly membrane-bound CEACAM proteins. PSGs are …

Roles of N-linked glycosylation and glycan-binding proteins in placentation: trophoblast infiltration, immunomodulation, angiogenesis, and pathophysiology

Z Huang, PF Lai, ATH Cocker… - Biochemical Society …, 2023 - portlandpress.com
Protein N-linked glycosylation is a structurally diverse post-translational modification that
stores biological information in a larger order of magnitude than other post-translational …

[HTML][HTML] Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-β and prevents dextran sodium sulfate (DSS)-induced colitis in mice

SM Blois, G Sulkowski, I Tirado-González, J Warren… - Mucosal …, 2014 - Elsevier
Transforming growth factor-βs (TGF-βs) are secreted from cells as latent complexes and the
activity of TGF-βs is controlled predominantly through activation of these complexes …

[HTML][HTML] Shotgun proteomics of thyroid carcinoma exosomes–Insight into the role of exosomal proteins in carcinogenesis and thyroid homeostasis

M Surman, M Wilczak, U Jankowska… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background Transport of molecules via exosomes is one of the factors involved in thyroid
cancer development, and transported molecules may serve as cancer biomarkers. The aim …

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet—fibrinogen interaction

DK Shanley, PA Kiely, K Golla, S Allen, K Martin… - PloS one, 2013 - journals.plos.org
Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members
encoded by multigene families in rodents and primates. In human pregnancy, PSGs are …